T0KBY6 · T0KBY6_COLGC

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Pathway

Protein modification; protein glycosylation.

Features

Showing features for active site, binding site.

160450100150200250300350400450500550600
TypeIDPosition(s)Description
Active site197Proton donor
Active site331
Active site447Proton donor
Active site491
Binding site580Ca2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentmembrane
Molecular Functioncalcium ion binding
Molecular Functionmannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Biological Processcarbohydrate metabolic process
Biological Processmannose trimming involved in glycoprotein ERAD pathway
Biological Processprotein glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    alpha-1,2-Mannosidase
  • EC number

Gene names

    • ORF names
      CGLO_07430

Organism names

Accessions

  • Primary accession
    T0KBY6

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond404↔433

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region69-111Disordered
Compositional bias94-111Basic and acidic residues

Sequence similarities

Belongs to the glycosyl hydrolase 47 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    604
  • Mass (Da)
    68,646
  • Last updated
    2013-10-16 v1
  • Checksum
    D0791AAF2F2AF665
MITIRRRPARLPIYLGIALTLLFLWQTGLPAGWSARELSFNGIRYRKSSYDWGSLNLEYPLEKPLRTLPKGKPVDLPPVQYDFGTSGKKSNKKNKKLSHDEDRDREHEKQIESRRAAVVNAFRRSWDSYKQHAWTWDELTPVTGAGKNTFGGWAASMVDGLDSLWIMGMHDEFRRAVRTVALIDWSNTTESAANMFETTIRHLGGLISAYDLSSEPALLAKAIELGDMLYMGFDTPNRMPPFWFKFSDAKYGTQKVGERESSAAGCSLSMEFTRLSQITGDPKYYDATERVKEFLVKTQPDTKLPGMWPMFMNYREEKADESSFTIGAQADSLYEYLPKMHALLGGLDSEYEKLTTSSFDVINKHILFRPILPNKTDILIPGNVFAHGSAHSVDLTPEAQHLGCFAGAMYGLAGKLLSSDSYVNIGERISRGCAWAYKVFPTGIMPEIMTLHPCNEPDHGACEWDEKAYGRSDVPAGVKQVRDGRYMLRPEAIESIFYMYRITGDEEWRDTAWDMFQAIQRATETPLAYSAISNVNVPYAEMTTKTDSMESFWFSETLKYFYLIFSPPDIISLDDWVLNTEAHPFKRPKRTHSVETEAELRGQS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias94-111Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AMYD01001493
EMBL· GenBank· DDBJ
EQB52907.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp