S9UY62 · S9UY62_9TRYP
- ProteinAlkylglycerone-phosphate synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids645 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
Catalytic activity
- a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H+
Cofactor
Pathway
Glycerolipid metabolism; ether lipid biosynthesis.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 230-236 | FAD (UniProtKB | ChEBI) | |||
Binding site | 293-299 | FAD (UniProtKB | ChEBI) | |||
Site | 344 | Important for enzyme activity | |||
Binding site | 440 | substrate | |||
Active site | 501 | Proton donor/acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | alkylglycerone-phosphate synthase activity | |
Molecular Function | FAD binding | |
Biological Process | lipid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkylglycerone-phosphate synthase
- EC number
- Short namesAlkyl-DHAP synthase
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Strigomonadinae > Strigomonas
Accessions
- Primary accessionS9UY62
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length645
- Mass (Da)72,134
- Last updated2013-10-16 v1
- MD5 Checksum844B729A5C0851E1DEE6560D51288993
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ATMH01006746 EMBL· GenBank· DDBJ | EPY25497.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
ATMH01002102 EMBL· GenBank· DDBJ | EPY33664.1 EMBL· GenBank· DDBJ | Genomic DNA |