S9U1T5 · S9U1T5_9TRYP
- Protein2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids256 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
Catalytic activity
- a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+
a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol RHEA-COMP:10858 + CHEBI:59789 = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol RHEA-COMP:10859 + CHEBI:57856 + CHEBI:15378
Pathway
Cofactor biosynthesis; ubiquinone biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 81 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 102 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 128-129 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 145 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extrinsic component of mitochondrial inner membrane | |
Molecular Function | 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Strigomonadinae > Strigomonas
Accessions
- Primary accessionS9U1T5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Subunit
Component of a multi-subunit COQ enzyme complex.
Structure
Sequence
- Sequence statusComplete
- Length256
- Mass (Da)29,302
- Last updated2013-10-16 v1
- Checksum8BAD25054C520CD5
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ATMH01008071 EMBL· GenBank· DDBJ | EPY22888.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
ATMH01005805 EMBL· GenBank· DDBJ | EPY27330.1 EMBL· GenBank· DDBJ | Genomic DNA |