S9R0P6 · S9R0P6_9RHOB
- ProteinSerine--tRNA ligase
- GeneserS
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids466 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
Catalytic activity
- tRNA(Sec) + L-serine + ATP = L-seryl-tRNA(Sec) + AMP + diphosphate + H+
Pathway
Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 266 | L-serine (UniProtKB | ChEBI) | |||
Binding site | 266-268 | L-serine (UniProtKB | ChEBI) | |||
Binding site | 297 | L-serine (UniProtKB | ChEBI) | |||
Binding site | 297-299 | ATP (UniProtKB | ChEBI) | |||
Binding site | 320 | L-serine (UniProtKB | ChEBI) | |||
Binding site | 384-387 | ATP (UniProtKB | ChEBI) | |||
Binding site | 418 | L-serine (UniProtKB | ChEBI) | |||
Binding site | 420 | L-serine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | serine-tRNA ligase activity | |
Biological Process | selenocysteine biosynthetic process | |
Biological Process | seryl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Roseobacteraceae > Rubellimicrobium
Accessions
- Primary accessionS9R0P6
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer. The tRNA molecule binds across the dimer.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-34 | Disordered | |||
Compositional bias | 18-32 | Polar residues | |||
Coiled coil | 105-139 | ||||
Domain | 208-445 | Aminoacyl-transfer RNA synthetases class-II family profile | |||
Domain
Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length466
- Mass (Da)51,054
- Last updated2013-10-16 v1
- Checksum7FCE31E537B73F6B
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 18-32 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AOLV01000008 EMBL· GenBank· DDBJ | EPX87201.1 EMBL· GenBank· DDBJ | Genomic DNA |