S5NAL0 · S5NAL0_SALBN
- ProteinPyruvate dehydrogenase E1 component
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids887 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
Catalytic activity
- H+ + N6-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate = CO2 + N6-[(R)-S8-acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]
Cofactor
Protein has several cofactor binding sites:
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | pyruvate dehydrogenase (acetyl-transferring) activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyruvate dehydrogenase E1 component
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionS5NAL0
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 105-294 | Transketolase N-terminal | ||||
Sequence: GGHMASFQSSATIYEVCFNHFFRARNEQDGGDLVYFQGHISPGIYARAFVEGRLTQEQMDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIVNELEGIFEGAGWNVIKVM | ||||||
Domain | 488-700 | Pyruvate dehydrogenase E1 component middle | ||||
Sequence: EQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEKQENIYYYITTLNENYHMP |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length887
- Mass (Da)99,772
- Last updated2013-10-16 v1
- ChecksumBD2191B37119AB3A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP006608 EMBL· GenBank· DDBJ | AGR57342.1 EMBL· GenBank· DDBJ | Genomic DNA |