S5N300 · S5N300_SALBN

  • Protein
    4-hydroxybenzoate octaprenyltransferase
  • Gene
    ubiA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function4-hydroxybenzoate decaprenyltransferase activity
Molecular Function4-hydroxybenzoate nonaprenyltransferase activity
Molecular Function4-hydroxybenzoate octaprenyltransferase activity
Biological Processubiquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxybenzoate octaprenyltransferase
  • EC number
  • Alternative names
    • 4-HB polyprenyltransferase

Gene names

    • Name
      ubiA
    • ORF names
      A464_4225

Organism names

  • Taxonomic identifier
  • Strain
    • N268-08
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella

Accessions

  • Primary accession
    S5N300

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane21-40Helical
Transmembrane46-70Helical
Transmembrane99-132Helical
Transmembrane144-162Helical
Transmembrane213-232Helical
Transmembrane269-288Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the UbiA prenyltransferase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    290
  • Mass (Da)
    32,318
  • Last updated
    2013-10-16 v1
  • Checksum
    5ABC2257E3F0262A
MEWSLTQSKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGMPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARNLFIVLVLLAFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESTPLSCWLMFLANILWAVAYDTQYAMVDRDDDIKIGIKSTAILFGRYDKLIIGILQLGVLALMALIGGLNGLGGGYYWSVLVAGALFAYQQKLIASREREACFKAFMNNNYVGLVLFLGLAMSYWHF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP006608
EMBL· GenBank· DDBJ
AGR61408.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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