S5MT45 · S5MT45_SALBN

Function

function

Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).

Pathway

Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.

Features

Showing features for active site, site.

TypeIDPosition(s)Description
Active site72Proton acceptor; for enolization step
Active site141For ring-opening step
Active site143Proton acceptor; for ring-opening step
Active site148For ring-opening step
Site151Part of the allosteric site
Site158Part of the allosteric site
Site160Part of the allosteric site
Site161Part of the allosteric site

GO annotations

AspectTerm
Molecular Functionglucosamine-6-phosphate deaminase activity
Biological Processcarbohydrate metabolic process
Biological ProcessN-acetylglucosamine metabolic process
Biological ProcessN-acetylneuraminate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucosamine-6-phosphate deaminase
  • EC number
  • Alternative names
    • GlcN6P deaminase
      (GNPDA
      )
    • Glucosamine-6-phosphate isomerase

Gene names

    • Name
      nagB
    • ORF names
      A464_643

Organism names

  • Taxonomic identifier
  • Strain
    • N268-08
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella

Accessions

  • Primary accession
    S5MT45

Proteomes

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-229Glucosamine/galactosamine-6-phosphate isomerase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    266
  • Mass (Da)
    29,646
  • Last updated
    2013-10-16 v1
  • Checksum
    86B779A716219C61
MRLIPLSTAEQVGKWAARHIVKRINAFKPTADRPFVLGLPTGGTPLTAYKALVEMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYHSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDGDVNQVPKYALTVGVGTLLDAEEVMILVLGHQKAQALQAAVEGNVNHMWTISCLQLHPKAVVVCDEPSTMELKVKTLKYFNELEAENIKGL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP006608
EMBL· GenBank· DDBJ
AGR57829.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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