S4XK25 · S4XK25_SORCE

  • Protein
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • Gene
    hppA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site458Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      SCE1572_06555

Organism names

Accessions

  • Primary accession
    S4XK25

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-23Helical
Transmembrane58-79Helical
Transmembrane125-148Helical
Transmembrane154-172Helical
Transmembrane230-247Helical
Transmembrane267-286Helical
Transmembrane298-318Helical
Transmembrane324-348Helical
Transmembrane369-393Helical
Transmembrane399-420Helical
Transmembrane464-484Helical
Transmembrane496-519Helical
Transmembrane574-592Helical
Transmembrane598-617Helical
Transmembrane665-683Helical

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    684
  • Mass (Da)
    69,125
  • Last updated
    2013-10-16 v1
  • Checksum
    D61402983A183665
MDALSYQSLVTGAVALVVARTFYVRVKKAPEGNETMARIARYVREGAMAFLAREYKVLAVYAAVVFALLAATLGLLAAGAFASGAFLSLIAGFFGMKAATYANVRTAEAARAHGKPTALVTALDGGAVMGLCVAGLGLIGLGGIYALFRNHEHLATVVHSFAVGASSIALFARIGGGIYTKAADVGADIVGKVEANIPEDDPRNPGVIADNVGDNVGDIAGMGADIYESYVAAVVAAIALGLTMPIAKLQQLAPSAGEVELRAMAVSLPLLLATIGLAVSVVGIFITRALKNLPPARVLRLALIVPPFLVVLAAAVILPELGFSFGAVITLAAGAAGGAIVGLVTDYYTSMGPIHKVAQSSLTGPGTNVIRGIAVGLESVAIPLMTLVAVGWISNHYLGLYGIALAAVGMLAGTAIVMTVDAYGPIADNGGGISEMAGLGKEVRAITDELDAVGNTTAAVGKGFAIGSAVLTVVALFAAFNMEVDAVRRAKGLPELVLYLTDAKVLMGLLFGALLPCLVGSLTMTAVGRAAGSIVEEIRRQFREIPGLLEGKPGVDPQPKVIVDIATTAAIREMIAPGAIAVLAPVVVGFVAGPEVLAGTLAGALVVGAVLSLMMANGGGAWDNAKKHIEKGGLDGHAKGSDAHKAAVVGDTVGDPFKDTSGPGISILIKVMGVVSLLIAPLIA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003969
EMBL· GenBank· DDBJ
AGP32150.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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