S3CBY5 · S3CBY5_OPHP1

Function

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionmevalonate kinase activity
Molecular Functionprotein prenyltransferase activity
Biological Processergosterol biosynthetic process
Biological Processisopentenyl diphosphate biosynthetic process, mevalonate pathway
Biological Processphosphorylation
Biological Processprotein prenylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    mevalonate kinase
  • EC number

Gene names

    • ORF names
      F503_05507

Organism names

Accessions

  • Primary accession
    S3CBY5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain165-242GHMP kinase N-terminal
Region318-354Disordered
Compositional bias329-343Polar residues
Domain358-422GHMP kinase C-terminal
Region506-562Disordered
Region636-660Disordered
Compositional bias639-653Pro residues

Sequence similarities

Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,077
  • Mass (Da)
    119,012
  • Last updated
    2013-09-18 v1
  • MD5 Checksum
    AED6589AA26B3AC20282BE2874AB91C1
MSTETTPESTLALRYRMNRKQSSPMMPAFMVSAPGKVIVFGEHSVVHGKAAVAAAISLRSYLLVTSLSKSRRTVTLRFPDIDMSHTWNIDELPWASFSKPGKKKSYYDLVTSLDPELLDAVEPHLAEVSPAKSEHERKVHQSSALSFLYLFLSLGSQKFPGCVYTLRSTLPIGAGLGSSGSIAVCMATALLLQIRTLSGPHPDQPSDEAKLQIERINRWAFVAEMCIHGNPSGVDNTVSTQGKAVVFQRTDYSKPPSVKPLWNFPELPLLLVDTKQPKSTKFEVAKVARLKRREPLLVGNILNAMDSVARSAIAAIENTGESDSGESDTDASSESNAPVNGNTQVGEEDDEDDKLDQMSKIGQLMTVNHGLLYALGVSHPRLERVRELVDHEGIGYTKLTGAGGGGCSITLMKPDAPPEKVAKLEQQLEAEGYGKFVTTLGGDGVGVLWPAVLRNGLDEDEEGGMEIDVEKFLNAKGNEGVESLVGVLGNNACSPAVSTTLFSNSLSVSEQRNQREENSIKVTNRQTMPPKSKAAPKAKEIKETQPAVQPPRTVEERSQERYYQSRPYARAVDKDGVSGLSPADRIAWASSQLLNAASASSSARNGRHLLSNKAHKDLWRYINEASLPLRCLKQPAPAPAGGAQPPLPLPGAKPAPGGIWGRDRSGRYVGEYTFDEFQLRAEKRVRLSSLEVAHQVFVAKREAGNTTPQDITEEKQRRADIAVLKMELYGQRAGGSYSQDPEWDDVEPIALVEPEGALAAIAYPEAYSEAISYLRAVMTKPEYSARSLRLTEHIISLNPAHYTVWLYRFSIVKALKISVEDETAWLNEVALQNLKNYQIWHHRFLLAECYYPQIAGSPERVTEFARSEMDFLTTILAEDTKNYHVWSYRQYLVRKLGYWTDAERIAVEAFIRQDVRNNSAWSHRFFLVFSDPKQSTNVASNEADTKTLEASVGELNISHDPKVPAVVLDREIGYAQEQITKAPQNESPWNYLRGVLTKGGRSLATMEEFALQFVANIGSTDSEAAEVVTSTHAMDVLVSVYAETGDKAKAEVFLDRLSDKWDPIRAGYWRYRKQQLV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias329-343Polar residues
Compositional bias639-653Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KE148146
EMBL· GenBank· DDBJ
EPE10412.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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