S3BPR1 · S3BPR1_OPHP1

Function

function

May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcatalytic step 2 spliceosome
Molecular Functionpeptidyl-prolyl cis-trans isomerase activity
Molecular Functionubiquitin protein ligase activity
Biological Processprotein folding
Biological Processprotein peptidyl-prolyl isomerization
Biological Processprotein polyubiquitination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peptidyl-prolyl cis-trans isomerase-like 2
  • EC number
  • Alternative names
    • Cyclophilin-60
    • Cyclophilin-like protein Cyp-60
    • RING-type E3 ubiquitin transferase isomerase-like 2

Gene names

    • ORF names
      F503_02032

Organism names

Accessions

  • Primary accession
    S3BPR1

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain44-121U-box
Region195-217Disordered
Region235-279Disordered
Domain335-482PPIase cyclophilin-type
Compositional bias497-530Basic and acidic residues
Region497-588Disordered
Compositional bias554-577Basic and acidic residues

Sequence similarities

Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    588
  • Mass (Da)
    64,509
  • Last updated
    2013-09-18 v1
  • Checksum
    54B4A7256A1DC9D0
MGKGTDKLYITHSEWASSDAFSASKGNVGRTGLATLPNNGASFRRLPFNYCAASLQPFAHPVCTPDGTIFDAEVIAAWIEKQKPKQATNPINGQPLKASDLIRLNFARNDADGSGDLIDPVTFKIFTDNTHIVALRHGTYANVFAWDTIERMNIKPKMWLDLVDDAEFTRKDIITLQDPQNVAGRDMSQFKFVKEGKEAAPAPNADHDDEADGGSVNINALGRIGEKVLRAKEAVEKARRERNAGGDVNRSTSSAIAKSGSKGTVAPIQPADRSASTIKQKPAYNAASYTTGRAAASFTSTGLTPETSGERAVLTDEEWMLVPKRIKIKGYARLETNLGNLNIELQTETAPKAVWNFVRLAQKGFYKGVVFHRSIRKFMIQGGDPTGTGRGGTSIWGKNFACELEGPLTHSQRGVLSMANKGKDTNSSQFFITYGPAKHLDRKHTIFGQVIDGMDVLDRMEATPVGKGDRPVNDIVIKDVVVYIDPFQEFLAEKQKTEKEDAKKAEIQRQGGADDDKFTWTGKRLRGTDDSAKSGAGVGKYLKTALKQQQQQQQEPHDETREGVYTESWEEPASKKAKKSGFGNFDAW

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias497-530Basic and acidic residues
Compositional bias554-577Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KE148169
EMBL· GenBank· DDBJ
EPE03294.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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