S0ENH1 · FUS7_GIBF5
- ProteinPutative aldehyde dehydrogenase FUS7
- GeneFUS7
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids461 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Putative aldehyde dehydrogenase; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:23932525).
Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (PubMed:23932525).
The other FUS cluster members are not essential for fusarin C biosynthesis (PubMed:23932525).
Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (PubMed:23932525).
The other FUS cluster members are not essential for fusarin C biosynthesis (PubMed:23932525).
Catalytic activity
- an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 220-225 | NAD+ (UniProtKB | ChEBI) | |||
Active site | 242 | ||||
Active site | 276 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aldehyde dehydrogenase (NAD+) activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative aldehyde dehydrogenase FUS7
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium fujikuroi species complex
Accessions
- Primary accessionS0ENH1
Proteomes
Organism-specific databases
Phenotypes & Variants
Disruption phenotype
Does not alter fusarin C production (PubMed:23932525).
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000437365 | 1-461 | Putative aldehyde dehydrogenase FUS7 | ||
Expression
Induction
Expressed under high amounts of nitrogen via regulation by GLN1 (PubMed:23932525).
Moreover, components of the fungal-specific velvet complex VEL1, VEL2 and LAE1 act also as positive regulators of expression (PubMed:20572938, PubMed:23932525).
Finally, expression is induced under acidic conditions in a PACC-independent manner (PubMed:23932525).
Moreover, components of the fungal-specific velvet complex VEL1, VEL2 and LAE1 act also as positive regulators of expression (PubMed:20572938, PubMed:23932525).
Finally, expression is induced under acidic conditions in a PACC-independent manner (PubMed:23932525).
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length461
- Mass (Da)49,998
- Last updated2013-09-18 v1
- MD5 Checksum68B1D044361140D5B013767F69D06803
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
HF679031 EMBL· GenBank· DDBJ | CCT74093.1 EMBL· GenBank· DDBJ | Genomic DNA |