Essential maintenance is planned to begin on Tue Jan 28 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ during this time.

S0ENH1 · FUS7_GIBF5

Function

function

Putative aldehyde dehydrogenase; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:23932525).
Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (PubMed:23932525).
The other FUS cluster members are not essential for fusarin C biosynthesis (PubMed:23932525).

Catalytic activity

Features

Showing features for binding site, active site.

146150100150200250300350400450
Type
IDPosition(s)Description
Binding site220-225NAD+ (UniProtKB | ChEBI)
Active site242
Active site276

GO annotations

AspectTerm
Molecular Functionaldehyde dehydrogenase (NAD+) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative aldehyde dehydrogenase FUS7
  • EC number
  • Alternative names
    • Fusarin biosynthesis protein 7

Gene names

    • Name
      FUS7
    • ORF names
      FFUJ_10052

Organism names

Accessions

  • Primary accession
    S0ENH1

Proteomes

Organism-specific databases

Phenotypes & Variants

Disruption phenotype

Does not alter fusarin C production (PubMed:23932525).

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004373651-461Putative aldehyde dehydrogenase FUS7

Expression

Induction

Expressed under high amounts of nitrogen via regulation by GLN1 (PubMed:23932525).
Moreover, components of the fungal-specific velvet complex VEL1, VEL2 and LAE1 act also as positive regulators of expression (PubMed:20572938, PubMed:23932525).
Finally, expression is induced under acidic conditions in a PACC-independent manner (PubMed:23932525).

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    461
  • Mass (Da)
    49,998
  • Last updated
    2013-09-18 v1
  • MD5 Checksum
    68B1D044361140D5B013767F69D06803
MSFDTFYNIITGQPRSARETTSGVNPLDRSSLWPAPVATGNDVEEAVRSAQEAFPAWSEKTYKQRTELLEKFADLYLVHANEFCQLIATECGRTAGNAAIEVYVAAQWLRYPSKYEIPEEVTEDEKKTSIVTHEPLGVVAAICPWNFPLMLALGKIAPALATGNCVILKPSPFTPYSSLKLVELAQQVFPPSVLQVLHGHDDLGPMLVKHPRIQKITFTGSTTTGKQILRDAAETMKRVTLETAGNNASIILPDVNIEAVIPQLAGGLWFNAGQVCIATRRMYIHQDIFDEAVAQLAEASKDLASGMEPIQNEMQLVRLQQALSDANAAGCELLSLGKTEAAEGFFIQPTILKSPPPDADVVQQENFGPIVSCIKFSSLDEAISLANNSDTGLAASVWSSDVSAARRVAAKLEVGNVYINGPPQPDPYVPFGGHKQSGLGVEYGLPGLLSFCQTKSTYLYK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HF679031
EMBL· GenBank· DDBJ
CCT74093.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help