S0B1K5 · S0B1K5_ENTIV
- ProteinGlyceraldehyde-3-phosphate dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids334 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- D-glyceraldehyde 3-phosphate + NAD+ + phosphate = (2R)-3-phospho-glyceroyl phosphate + H+ + NADH
Pathway
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 12-13 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: RI | ||||||
Binding site | 34 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 79 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 121 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 150-152 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: SCT | ||||||
Active site | 151 | Nucleophile | ||||
Sequence: C | ||||||
Site | 178 | Activates thiol group during catalysis | ||||
Sequence: H | ||||||
Binding site | 181 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 210-211 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: TG | ||||||
Binding site | 233 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 315 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: N |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | glucose metabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlyceraldehyde-3-phosphate dehydrogenase
- EC number
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Amoebozoa > Evosea > Archamoebae > Mastigamoebida > Entamoebidae > Entamoeba
Accessions
- Primary accessionS0B1K5
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-151 | Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding | ||||
Sequence: IKVGINGFGRIGRLVARVILSRPEFELVALNDPFMDPKYMEYMLKYDTVHGKFPGTVAVEEGNLVVDGHKIIVKAERDPAQIEWGTLGVDYVVESTGVFTTIPKCEAHIKGGAKKVIISAPSADAPMFVVGVNTEAYKPEMNVLSNASC |
Sequence similarities
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length334
- Mass (Da)36,070
- Last updated2013-09-18 v1
- ChecksumA51EE8E2A2A67CAE