R9QE65 · R9QE65_HUMAN
- ProteinSignal transducer and activator of transcription
- GeneSTAT2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids851 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | |
Biological Process | cell surface receptor signaling pathway via JAK-STAT | |
Biological Process | regulation of cell population proliferation | |
Biological Process | response to peptide hormone | |
Biological Process | type I interferon-mediated signaling pathway |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSignal transducer and activator of transcription
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionR9QE65
Organism-specific databases
Disease & Variants
Organism-specific databases
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 572-667 | SH2 | ||||
Sequence: WNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPR |
Sequence similarities
Belongs to the transcription factor STAT family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length851
- Mass (Da)97,916
- Last updated2013-09-18 v1
- ChecksumE4C74674CB7A3215
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JX178204 EMBL· GenBank· DDBJ | AFM91192.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178205 EMBL· GenBank· DDBJ | AFM91193.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178206 EMBL· GenBank· DDBJ | AFM91194.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178208 EMBL· GenBank· DDBJ | AFM91197.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178209 EMBL· GenBank· DDBJ | AFM91198.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178210 EMBL· GenBank· DDBJ | AFM91199.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178211 EMBL· GenBank· DDBJ | AFM91200.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178213 EMBL· GenBank· DDBJ | AFM91202.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178214 EMBL· GenBank· DDBJ | AFM91203.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178215 EMBL· GenBank· DDBJ | AFM91204.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178216 EMBL· GenBank· DDBJ | AFM91205.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178217 EMBL· GenBank· DDBJ | AFM91206.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178218 EMBL· GenBank· DDBJ | AFM91207.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178219 EMBL· GenBank· DDBJ | AFM91208.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178220 EMBL· GenBank· DDBJ | AFM91209.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178223 EMBL· GenBank· DDBJ | AFM91212.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178224 EMBL· GenBank· DDBJ | AFM91213.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178225 EMBL· GenBank· DDBJ | AFM91214.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178227 EMBL· GenBank· DDBJ | AFM91216.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178232 EMBL· GenBank· DDBJ | AFM91221.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178234 EMBL· GenBank· DDBJ | AFM91223.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178236 EMBL· GenBank· DDBJ | AFM91225.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178237 EMBL· GenBank· DDBJ | AFM91226.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178238 EMBL· GenBank· DDBJ | AFM91227.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178239 EMBL· GenBank· DDBJ | AFM91228.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178240 EMBL· GenBank· DDBJ | AFM91229.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178241 EMBL· GenBank· DDBJ | AFM91230.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178242 EMBL· GenBank· DDBJ | AFM91231.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178243 EMBL· GenBank· DDBJ | AFM91232.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178245 EMBL· GenBank· DDBJ | AFM91234.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178246 EMBL· GenBank· DDBJ | AFM91235.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178247 EMBL· GenBank· DDBJ | AFM91236.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178249 EMBL· GenBank· DDBJ | AFM91238.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178250 EMBL· GenBank· DDBJ | AFM91239.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178251 EMBL· GenBank· DDBJ | AFM91240.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178252 EMBL· GenBank· DDBJ | AFM91241.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178254 EMBL· GenBank· DDBJ | AFM91243.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178255 EMBL· GenBank· DDBJ | AFM91244.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178256 EMBL· GenBank· DDBJ | AFM91245.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178257 EMBL· GenBank· DDBJ | AFM91246.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178258 EMBL· GenBank· DDBJ | AFM91247.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178260 EMBL· GenBank· DDBJ | AFM91249.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178262 EMBL· GenBank· DDBJ | AFM91251.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178263 EMBL· GenBank· DDBJ | AFM91252.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178264 EMBL· GenBank· DDBJ | AFM91253.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178266 EMBL· GenBank· DDBJ | AFM91255.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178269 EMBL· GenBank· DDBJ | AFM91258.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX178273 EMBL· GenBank· DDBJ | AFM91262.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH471054 EMBL· GenBank· DDBJ | EAW96934.1 EMBL· GenBank· DDBJ | Genomic DNA |