R4YZ55 · R4YZ55_9ACTN
- ProteinProtein-L-isoaspartate O-methyltransferase
- Genepcm
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids214 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Catalytic activity
- [protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 52 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity | |
Biological Process | methylation | |
Biological Process | protein modification process | |
Biological Process | protein repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein-L-isoaspartate O-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Acidimicrobiia > Acidimicrobiales > Microthrixaceae > Candidatus Microthrix
Accessions
- Primary accessionR4YZ55
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length214
- Mass (Da)22,646
- Last updated2013-07-24 v1
- ChecksumE71BC22857F4F106
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CANL01000022 EMBL· GenBank· DDBJ | CCM63685.1 EMBL· GenBank· DDBJ | Genomic DNA |