R4G4C9 · R4G4C9_RHOPR
- ProteinHomogentisate 1,2-dioxygenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids448 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Cofactor
Pathway
Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 302 | Proton acceptor | |||
Binding site | 345 | Fe cation (UniProtKB | ChEBI) | |||
Binding site | 351 | Fe cation (UniProtKB | ChEBI) | |||
Binding site | 360 | homogentisate (UniProtKB | ChEBI) | |||
Binding site | 381 | Fe cation (UniProtKB | ChEBI) | |||
Binding site | 381 | homogentisate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | homogentisate 1,2-dioxygenase activity | |
Molecular Function | metal ion binding | |
Biological Process | L-phenylalanine catabolic process | |
Biological Process | tyrosine metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomogentisate 1,2-dioxygenase
- EC number
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Heteroptera > Panheteroptera > Cimicomorpha > Reduviidae > Triatominae > Rhodnius
Accessions
- Primary accessionR4G4C9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 7-289 | Homogentisate 1,2-dioxygenase N-terminal | |||
Domain | 290-441 | Homogentisate 1,2-dioxygenase C-terminal | |||
Sequence similarities
Belongs to the homogentisate dioxygenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length448
- Mass (Da)51,104
- Last updated2013-06-26 v1
- MD5 ChecksumBEAE77B00F9AAC43FB1C799D9B074572
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ACPB03017824 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KX572143 EMBL· GenBank· DDBJ | ANZ03347.1 EMBL· GenBank· DDBJ | mRNA | ||
GAHY01001475 EMBL· GenBank· DDBJ | JAA76035.1 EMBL· GenBank· DDBJ | mRNA |