R0BUD0 · R0BUD0_9FIRM

Function

function

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionpenicillin binding
Molecular Functionpeptidoglycan glycosyltransferase activity
Molecular Functionserine-type D-Ala-D-Ala carboxypeptidase activity
Biological Processpeptidoglycan biosynthetic process
Biological Processproteolysis
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Penicillin-binding protein 1A
  • EC number

Gene names

    • ORF names
      HMPREF1085_00939

Organism names

  • Taxonomic identifier
  • Strain
    • 90A9
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Enterocloster

Accessions

  • Primary accession
    R0BUD0

Proteomes

Subcellular Location

Cell membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane26-53Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain86-269Glycosyl transferase family 51
Domain448-706Penicillin-binding protein transpeptidase
Compositional bias859-889Polar residues
Region859-897Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    897
  • Mass (Da)
    98,079
  • Last updated
    2013-06-26 v1
  • Checksum
    BB70AB77A65F1580
MNYGKYEAERRLKSLHSKSGKYASRLLLNIFKALFVLFLFLAVVGASIGFGMVKGIIDNAPSVDILNIQPSRFATAVYDSAGNLTDTLVTSGSNREEATYEELPKDLINAFVAIEDSRFWSHNGIDIRSIARAVKGIVSDDYAGGGSTITQQLIKNNVFSGGMESGWGARIERKLQEQYLAVQLEKNSGMSKEDTKKLIITNYLNTINLGNNTLGVKVAAKRYFNKDVSDLTLSECTVLASITKNPSRLNPISGRENNAERRRIVLQYMYEQGYITKAQQEEALADDVYDRIQNVDTAAKGTNSHYSYFTDELIEQVINELMDKLDYTESQASNLLYSGGLQIYTTQDPALQAIVDEEINNPDNYSVAKYSVEYRLSITHADGTTEHYSEENLRTFRKSVLGDSSFEGLYASKEAVQDDIDQYKAWLLKDGDEIIGERQNLILQPQASFVLLDQHTGEVKALCGGRGEKTASLTLNRASNVYRQPGSAFKVITAFAPALDACGATLGTVYYDAPYTIGTKTFRNWWNSGYGFTGYSSIRDGIIYSMNIVAVRCLMETVTPQLGVEYAENMGITSLTKDDLGAATALGGITKGVSNLELTTAYASIANGGVYTKPRFFTKILDHNGKVLIDNEPETKQVLKDSTAFLLTDAMSESMKSNRKFTRPGVSINSTSTRAALTGMTAAGKSGTTTSNNDVWFVGYTPYYTAGIWGGCDNNQKLKHGGVNNGGTTFHKDIWRNIMNRVHEGLSDPGFAVPDSIETAEICRKSGKRAVSGVCNHDPRGNAVYTEYFAKGTAPTEVCDKHVEVTVCAESGMRPTPYCPTKTTRVCMTLPEGEEGATDDSVFAIPGYCTIHSDVSTIIPPNTGDSDNTGPTVTPIGPGYQSPQESTEGFGPGNRPY

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias859-889Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGYH01000003
EMBL· GenBank· DDBJ
ENZ52223.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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