R0BU05 · R0BU05_9FIRM
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids694 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- Na+(in) + diphosphate + H2O = Na+(out) + 2 phosphate + H+Na+ (in)CHEBI:29101
+ CHEBI:33019 + CHEBI:15377 = Na+ (out)CHEBI:29101+ 2 CHEBI:43474 + CHEBI:15378
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 470 | Determinant of potassium dependence | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Enterocloster
Accessions
- Primary accessionR0BU05
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-25 | Helical | |||
Transmembrane | 57-79 | Helical | |||
Transmembrane | 85-103 | Helical | |||
Transmembrane | 124-151 | Helical | |||
Transmembrane | 163-185 | Helical | |||
Transmembrane | 267-285 | Helical | |||
Transmembrane | 305-323 | Helical | |||
Transmembrane | 329-351 | Helical | |||
Transmembrane | 372-400 | Helical | |||
Transmembrane | 412-431 | Helical | |||
Transmembrane | 475-493 | Helical | |||
Transmembrane | 513-533 | Helical | |||
Transmembrane | 580-600 | Helical | |||
Transmembrane | 606-625 | Helical | |||
Transmembrane | 672-693 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length694
- Mass (Da)71,339
- Last updated2013-06-26 v1
- ChecksumF7522A69A51FCC34
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGYH01000003 EMBL· GenBank· DDBJ | ENZ52123.1 EMBL· GenBank· DDBJ | Genomic DNA |