R0A5G7 · R0A5G7_9FIRM

Function

function

Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site150Zn2+ (UniProtKB | ChEBI)
Binding site153Zn2+ (UniProtKB | ChEBI)
Binding site167Zn2+ (UniProtKB | ChEBI)
Binding site170Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionmethionine-tRNA ligase activity
Molecular FunctiontRNA binding
Biological Processmethionyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methionine--tRNA ligase
  • EC number
  • Alternative names
    • Methionyl-tRNA synthetase
      (MetRS
      )

Gene names

    • Name
      metG
    • ORF names
      HMPREF1085_04500

Organism names

  • Taxonomic identifier
  • Strain
    • 90A9
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Enterocloster

Accessions

  • Primary accession
    R0A5G7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for motif, region, domain.

Type
IDPosition(s)Description
Motif35-45'HIGH' region
Motif322-326'KMSKS' region
Region548-569Disordered
Domain582-683TRNA-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    683
  • Mass (Da)
    77,050
  • Last updated
    2013-06-26 v1
  • Checksum
    1210C70D338F9B03
MNCSAPALCFRSEKEGINHMCQDCKKPYYITTAIAYASGKPHIGNTYEIILADSIARYKREQGYDVFFQTGTDEHGQKIEEKAEAAGVTPQEFVDKAAAEIKRIWDLMNTSYDKFIRTTDQDHEAQVQKIFKKLYDQGDIYKGYYEGLYCTPCESFFTESQLVDGKCPDCGREVKPAKEEAYFFRMSKYAPRLIEYINEHPEFIQPVSRKNEMMNNFLLPGLQDLCVSRTTFSWGIPVDFDPKHVTYVWLDALTNYITGIGYDCDGSSTDQFKKYWPADLHLIGKDIIRFHTIYWPIFLMALDVPLPKQVFGHPWLLQGDGKMSKSKGNVLYADTLVDFFGVDAVRYFVLHEMPFDNDGVISWELMVERMNSDLANILGNLVNRTISMSNKYFDGVVCDKGVCGEADEDLKKVVLEEVKKADAKMEQLRVADAMTEIFNIFRRCNKYIDETTPWTLAKDESQKDRLATVLYNLTEAIAIGASLLYSFMPETAEKILAQIHTDKRELSQMDAFGLYPNGQKVTDKPEILFARMDIKEVLEKVEAMHGAEAADQKQAGGQDGSSDNAEDSGIDLEAKPEITYDDFAKLQFQVGEIIKCEAVPKSKKLLCSQVKIGSQVRQILSGIKAYYSPEEMVGKKVMVVTNLKPAKLAGMVSEGMILCAEDAEGSLALMTPEKSMPAGAQIC

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGYH01000016
EMBL· GenBank· DDBJ
ENZ47321.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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