Q9ZUL5 · CHR19_ARATH
- ProteinProtein CHROMATIN REMODELING 19
- GeneETL1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids763 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs (By similarity).
Probable chromatin remodeling factor. Probable helicase-like transcription factor involved in transcriptional gene silencing. Associates with SUVR2 and contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. May be involved in nucleosome positioning to form ordered nucleosome arrays on chromatin (PubMed:25420628).
Probable chromatin remodeling factor. Probable helicase-like transcription factor involved in transcriptional gene silencing. Associates with SUVR2 and contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. May be involved in nucleosome positioning to form ordered nucleosome arrays on chromatin (PubMed:25420628).
Miscellaneous
Induction by the mutagens rose Bengal (RB) and methyl methane sulfonate (MMS) is enhanced in progeny of Chernobyl plants exposed to ionizing radiation thus leading to a higher resistance to DNA damages.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 239-246 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent chromatin remodeler activity | |
Molecular Function | DNA binding | |
Molecular Function | helicase activity | |
Molecular Function | hydrolase activity | |
Biological Process | cellular response to UV-C | |
Biological Process | DNA damage response | |
Biological Process | DNA repair | |
Biological Process | regulatory ncRNA-mediated gene silencing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein CHROMATIN REMODELING 19
- EC number
- Short namesAtCHR19
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9ZUL5
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000430856 | 1-763 | Protein CHROMATIN REMODELING 19 | ||
Proteomic databases
PTM databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, motif, coiled coil.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-43 | Disordered | |||
Region | 114-149 | Disordered | |||
Compositional bias | 116-131 | Acidic residues | |||
Domain | 226-404 | Helicase ATP-binding | |||
Motif | 353-356 | DEAH box | |||
Coiled coil | 462-482 | ||||
Motif | 520-527 | Nuclear localization signal | |||
Domain | 592-742 | Helicase C-terminal | |||
Sequence similarities
Belongs to the SNF2/RAD54 helicase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length763
- Mass (Da)86,277
- Last updated1999-05-01 v1
- MD5 Checksum281F4D194EF6381750308BBE4D801154
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 116-131 | Acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC005936 EMBL· GenBank· DDBJ | AAC97224.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC05545.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY059857 EMBL· GenBank· DDBJ | AAL24339.1 EMBL· GenBank· DDBJ | mRNA | ||
BT002576 EMBL· GenBank· DDBJ | AAO00936.1 EMBL· GenBank· DDBJ | mRNA |