Q9ZS91 · MSRB5_ARATH

Function

function

Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins. Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation. MSRB family specifically reduces the MetSO R-enantiomer (By similarity).

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

1139102030405060708090100110120130
Type
IDPosition(s)Description
Binding site51Zn2+ (UniProtKB | ChEBI)
Binding site54Zn2+ (UniProtKB | ChEBI)
Binding site97Zn2+ (UniProtKB | ChEBI)
Binding site100Zn2+ (UniProtKB | ChEBI)
Active site122Nucleophile

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionmetal ion binding
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peptide methionine sulfoxide reductase B5
  • EC number
  • Short names
    AtMSRB5
  • Alternative names
    • Peptide-methionine (R)-S-oxide reductase

Gene names

    • Name
      MSRB5
    • ORF names
      T4B21.5
    • Ordered locus names
      At4g04830

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9ZS91

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine, modified residue, chain, disulfide bond.

Type
IDPosition(s)Description
Initiator methionine1Removed
Modified residue2N-acetylalanine
ChainPRO_00003955232-139Peptide methionine sulfoxide reductase B5
Disulfide bond69↔122Redox-active

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain12-133MsrB

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

Q9ZS91-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    139
  • Mass (Da)
    15,251
  • Last updated
    1999-05-01 v1
  • Checksum
    6133EB2603675AF6
MAASPLVVQKTEEEWRAVLSPEQFRILRQKGTEKPGTGEYDKFFEEGIFDCVGCKTPLYKSTTKFDSGCGWPAFFEGLPGAINRTPDPDGRRTEITCAACDGHLGHVFKGEGYGNPTDERHCVNSVSISFNPAKSSSII

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F4JGY0F4JGY0_ARATHMSRB5129

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF118223
EMBL· GenBank· DDBJ
AAD03444.1
EMBL· GenBank· DDBJ
Genomic DNA
AL161501
EMBL· GenBank· DDBJ
CAB80848.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE82429.1
EMBL· GenBank· DDBJ
Genomic DNA
AY059946
EMBL· GenBank· DDBJ
AAL24428.1
EMBL· GenBank· DDBJ
mRNA
AY081609
EMBL· GenBank· DDBJ
AAM10171.1
EMBL· GenBank· DDBJ
mRNA
AY088697
EMBL· GenBank· DDBJ
AAM67017.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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