Q9ZRA2 · HGD_ARATH
- ProteinHomogentisate 1,2-dioxygenase
- GeneHGO
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids461 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- homogentisate + O2 = 4-maleylacetoacetate + H+
Cofactor
Pathway
Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plastid | |
Molecular Function | homogentisate 1,2-dioxygenase activity | |
Molecular Function | metal ion binding | |
Biological Process | homogentisate catabolic process | |
Biological Process | L-phenylalanine catabolic process | |
Biological Process | tyrosine catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomogentisate 1,2-dioxygenase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9ZRA2
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000220244 | 1-461 | Homogentisate 1,2-dioxygenase | |||
Sequence: MEEKKKELEELKYQSGFGNHFSSEAIAGALPLDQNSPLLCPYGLYAEQISGTSFTSPRKLNQRSWLYRVKPSVTHEPFKPRVPAHKKLVSEFDASNSRTNPTQLRWRPEDIPDSEIDFVDGLFTICGAGSSFLRHGFAIHMYVANTGMKDSAFCNADGDFLLVPQTGRLWIETECGRLLVTPGEIAVIPQGFRFSIDLPDGKSRGYVAEIYGAHFQLPDLGPIGANGLAASRDFLAPTAWFEDGLRPEYTIVQKFGGELFTAKQDFSPFNVVAWHGNYVPYKYDLKKFCPYNTVLLDHGDPSINTVLTAPTDKPGVALLDFVIFPPRWLVAEHTFRPPYYHRNCMSEFMGLIYGAYEAKADGFLPGGASLHSCMTPHGPDTTTYEATIARVNAMAPSKLTGTMAFMFESALIPRVCHWALESPFLDHDYYQCWIGLKSHFSRISLDKTNVESTEKEPGASE |
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length461
- Mass (Da)51,455
- Last updated2001-04-27 v2
- ChecksumCD90DD9638014D31
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 7 | in Ref. 6; AAM65958 | ||||
Sequence: E → K | ||||||
Sequence conflict | 69 | in Ref. 6; AAM65958 | ||||
Sequence: V → I | ||||||
Sequence conflict | 116 | in Ref. 6; AAM65958 | ||||
Sequence: I → T | ||||||
Sequence conflict | 146 | in Ref. 6; AAM65958 | ||||
Sequence: T → K | ||||||
Sequence conflict | 181 | in Ref. 6; AAM65958 | ||||
Sequence: T → S | ||||||
Sequence conflict | 231 | in Ref. 6; AAM65958 | ||||
Sequence: S → P | ||||||
Sequence conflict | 428 | in Ref. 1; AAD00360 | ||||
Sequence: D → E | ||||||
Sequence conflict | 452 | in Ref. 6; AAM65958 | ||||
Sequence: S → P |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U80668 EMBL· GenBank· DDBJ | AAD00360.1 EMBL· GenBank· DDBJ | mRNA | ||
AF130845 EMBL· GenBank· DDBJ | AAF36499.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB018115 EMBL· GenBank· DDBJ | BAA97130.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED96447.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED96448.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY140075 EMBL· GenBank· DDBJ | AAM98216.1 EMBL· GenBank· DDBJ | mRNA | ||
BT010329 EMBL· GenBank· DDBJ | AAQ55280.1 EMBL· GenBank· DDBJ | mRNA | ||
AY088421 EMBL· GenBank· DDBJ | AAM65958.1 EMBL· GenBank· DDBJ | mRNA |