Q9ZQ94 · U73C5_ARATH
- ProteinUDP-glycosyltransferase 73C5
- GeneUGT73C5
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids495 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Specifically catalyzes 23-O-glucosylation of brassinosteroids, resulting probably in their inactivation. Also, involved in the O-glucosylation of trans-zeatin and dihydrozeatin. Active in vitro on cis-zeatin, dihydrozeatin-9-N-Glc, and olomoucine. Also involved in the detoxification of the Fusarium mycotoxin deoxynivalenol by the transfer of glucose from UDP-glucose to the hydroxyl group at C-3. Possesses low quercetin 7-O-glucosyltransferase and 4'-O-glucosyltransferase activities in vitro.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 296 | UDP-alpha-D-glucose (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 356-358 | UDP-alpha-D-glucose (UniProtKB | ChEBI) | ||||
Sequence: SPQ | ||||||
Binding site | 373-381 | UDP-alpha-D-glucose (UniProtKB | ChEBI) | ||||
Sequence: HCGWNSTLE | ||||||
Binding site | 395-398 | UDP-alpha-D-glucose (UniProtKB | ChEBI) | ||||
Sequence: FADQ |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | membrane | |
Molecular Function | cis-zeatin O-beta-D-glucosyltransferase activity | |
Molecular Function | glucosyltransferase activity | |
Molecular Function | quercetin 4'-O-glucosyltransferase activity | |
Molecular Function | quercetin 7-O-glucosyltransferase activity | |
Molecular Function | trans-zeatin O-beta-D-glucosyltransferase activity | |
Molecular Function | UDP-glycosyltransferase activity | |
Biological Process | brassinosteroid metabolic process | |
Biological Process | cellular response to hypoxia | |
Biological Process | detoxification |
Keywords
- Molecular function
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameUDP-glycosyltransferase 73C5
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9ZQ94
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 146-162 | Helical | ||||
Sequence: ILFHGMGCFCLLCMHVL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000074157 | 1-495 | UDP-glycosyltransferase 73C5 | |||
Sequence: MVSETTKSSPLHFVLFPFMAQGHMIPMVDIARLLAQRGVIITIVTTPHNAARFKNVLNRAIESGLPINLVQVKFPYLEAGLQEGQENIDSLDTMERMIPFFKAVNFLEEPVQKLIEEMNPRPSCLISDFCLPYTSKIAKKFNIPKILFHGMGCFCLLCMHVLRKNREILDNLKSDKELFTVPDFPDRVEFTRTQVPVETYVPAGDWKDIFDGMVEANETSYGVIVNSFQELEPAYAKDYKEVRSGKAWTIGPVSLCNKVGADKAERGNKSDIDQDECLKWLDSKKHGSVLYVCLGSICNLPLSQLKELGLGLEESQRPFIWVIRGWEKYKELVEWFSESGFEDRIQDRGLLIKGWSPQMLILSHPSVGGFLTHCGWNSTLEGITAGLPLLTWPLFADQFCNEKLVVEVLKAGVRSGVEQPMKWGEEEKIGVLVDKEGVKKAVEELMGESDDAKERRRRAKELGDSAHKAVEEGGSSHSNISFLLQDIMELAEPNN |
Proteomic databases
PTM databases
Expression
Tissue specificity
Elongating hypocotyls and root-specific. Expressed in the vascular system, in meristematic tissues of the root tip, and in the vasculature of the hypocotyl right after germination. In late stage of flower development, expressed in petals, and in abscission zones.
Induction
Rapidly induced in response to deoxynivalenol exposure. Weak induction by salicylic acid, jasmonic acid and 1-aminocyclopropylcarbonic acid (ACC) treatments. Not induced by cytokinin treatment.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 446-471 | Basic and acidic residues | ||||
Sequence: MGESDDAKERRRRAKELGDSAHKAVE | ||||||
Region | 446-477 | Disordered | ||||
Sequence: MGESDDAKERRRRAKELGDSAHKAVEEGGSSH |
Sequence similarities
Belongs to the UDP-glycosyltransferase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length495
- Mass (Da)55,798
- Last updated1999-05-01 v1
- ChecksumAAC9727F48C069A9
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 446-471 | Basic and acidic residues | ||||
Sequence: MGESDDAKERRRRAKELGDSAHKAVE |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY573822 EMBL· GenBank· DDBJ | AAS87592.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AC006282 EMBL· GenBank· DDBJ | AAD20156.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC09299.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY062743 EMBL· GenBank· DDBJ | AAL32821.1 EMBL· GenBank· DDBJ | mRNA | ||
BT003373 EMBL· GenBank· DDBJ | AAO30036.1 EMBL· GenBank· DDBJ | mRNA |