Q9ZPW2 · APC10_ARATH

Function

function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating the ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several other aspects of development. Involved in the control of endoreduplication.

Pathway

Protein modification; protein ubiquitination.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentanaphase-promoting complex
Cellular Componentnuclear body
Biological Processanaphase-promoting complex-dependent catabolic process
Biological Processcell division
Biological Processnegative regulation of DNA endoreduplication
Biological Processphloem or xylem histogenesis
Biological Processprotein ubiquitination
Biological Processregulation of DNA endoreduplication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Anaphase-promoting complex subunit 10
  • Short names
    APC10
  • Alternative names
    • Cyclosome subunit 10

Gene names

    • Name
      APC10
    • ORF names
      T30D6.20
    • Ordered locus names
      At2g18290

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9ZPW2
  • Secondary accessions
    • Q1WWJ4
    • Q8LBL8

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001740141-192Anaphase-promoting complex subunit 10

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Component of the anaphase promoting complex/cyclosome (APC/C), which is composed of at least 10 subunits. Interacts with CDC20-1, CDC20-2, CDC27A and CDC27B.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q9ZPW2CDC27A Q06AN93EBI-1749354, EBI-1749373
BINARY Q9ZPW2CDC27B Q8LGU63EBI-1749354, EBI-1668733

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-192DOC

Sequence similarities

Belongs to the APC10 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    192
  • Mass (Da)
    21,750
  • Last updated
    2002-06-01 v2
  • Checksum
    5ADBE0E8F7D12FFC
MATESSESEEEGKISGGNYKLIIDDDLREMGKNAAWSVSSCKPGNGVTTLRDDNLETYWQSDGLQPHLINIQFQKKVKLQLVVLYVDFKLDESYTPSKISIRAGDGFHNLKEIKSVELVKPTGWVCLSLSGTDPRETFVNTFMLQIAILSNHLNGRDTHIRQIKVYGPRPNPIPHQPFQFTSMEFLTYSTLR

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict112in Ref. 3; AAM64688

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC006439
EMBL· GenBank· DDBJ
AAD15507.2
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06751.1
EMBL· GenBank· DDBJ
Genomic DNA
AY087130
EMBL· GenBank· DDBJ
AAM64688.1
EMBL· GenBank· DDBJ
mRNA
BT024912
EMBL· GenBank· DDBJ
ABD94068.1
EMBL· GenBank· DDBJ
mRNA
AK229538
EMBL· GenBank· DDBJ
BAF01391.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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