Q9ZPS9 · BRL2_ARATH
- ProteinSerine/threonine-protein kinase BRI1-like 2
- GeneBRL2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1143 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Receptor with a serine/threonine-protein kinase activity, which may transduce extracellular spatial and temporal signals into downstream cell differentiation responses in provascular and procambial cells. In contrast to BRI1, BRL1 and BRL3, it does not bind brassinolide.
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | transmembrane receptor protein serine/threonine kinase activity | |
Biological Process | auxin-activated signaling pathway | |
Biological Process | brassinosteroid mediated signaling pathway | |
Biological Process | leaf vascular tissue pattern formation | |
Biological Process | phloem transport | |
Biological Process | xylem and phloem pattern formation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase BRI1-like 2
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9ZPS9
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 32-756 | Extracellular | ||||
Sequence: DQSSLKTDSLSLLSFKTMIQDDPNNILSNWSPRKSPCQFSGVTCLGGRVTEINLSGSGLSGIVSFNAFTSLDSLSVLKLSENFFVLNSTSLLLLPLTLTHLELSSSGLIGTLPENFFSKYSNLISITLSYNNFTGKLPNDLFLSSKKLQTLDLSYNNITGPISGLTIPLSSCVSMTYLDFSGNSISGYISDSLINCTNLKSLNLSYNNFDGQIPKSFGELKLLQSLDLSHNRLTGWIPPEIGDTCRSLQNLRLSYNNFTGVIPESLSSCSWLQSLDLSNNNISGPFPNTILRSFGSLQILLLSNNLISGDFPTSISACKSLRIADFSSNRFSGVIPPDLCPGAASLEELRLPDNLVTGEIPPAISQCSELRTIDLSLNYLNGTIPPEIGNLQKLEQFIAWYNNIAGEIPPEIGKLQNLKDLILNNNQLTGEIPPEFFNCSNIEWVSFTSNRLTGEVPKDFGILSRLAVLQLGNNNFTGEIPPELGKCTTLVWLDLNTNHLTGEIPPRLGRQPGSKALSGLLSGNTMAFVRNVGNSCKGVGGLVEFSGIRPERLLQIPSLKSCDFTRMYSGPILSLFTRYQTIEYLDLSYNQLRGKIPDEIGEMIALQVLELSHNQLSGEIPFTIGQLKNLGVFDASDNRLQGQIPESFSNLSFLVQIDLSNNELTGPIPQRGQLSTLPATQYANNPGLCGVPLPECKNGNNQLPAGTEEGKRAKHGTRAASWANS | ||||||
Transmembrane | 757-777 | Helical | ||||
Sequence: IVLGVLISAASVCILIVWAIA | ||||||
Topological domain | 778-1143 | Cytoplasmic | ||||
Sequence: VRARRRDADDAKMLHSLQAVNSATTWKIEKEKEPLSINVATFQRQLRKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKLIRLSCQGDREFMAEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQYGSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLHHNCIPHIIHRDMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGDTNLVGWSKMKAREGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLRELRGSENNSHSHSNSL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, glycosylation, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-31 | |||||
Sequence: MTTSPIRVRIRTRIQISFIFLLTHLSQSSSS | ||||||
Chain | PRO_0000024309 | 32-1143 | Serine/threonine-protein kinase BRI1-like 2 | |||
Sequence: DQSSLKTDSLSLLSFKTMIQDDPNNILSNWSPRKSPCQFSGVTCLGGRVTEINLSGSGLSGIVSFNAFTSLDSLSVLKLSENFFVLNSTSLLLLPLTLTHLELSSSGLIGTLPENFFSKYSNLISITLSYNNFTGKLPNDLFLSSKKLQTLDLSYNNITGPISGLTIPLSSCVSMTYLDFSGNSISGYISDSLINCTNLKSLNLSYNNFDGQIPKSFGELKLLQSLDLSHNRLTGWIPPEIGDTCRSLQNLRLSYNNFTGVIPESLSSCSWLQSLDLSNNNISGPFPNTILRSFGSLQILLLSNNLISGDFPTSISACKSLRIADFSSNRFSGVIPPDLCPGAASLEELRLPDNLVTGEIPPAISQCSELRTIDLSLNYLNGTIPPEIGNLQKLEQFIAWYNNIAGEIPPEIGKLQNLKDLILNNNQLTGEIPPEFFNCSNIEWVSFTSNRLTGEVPKDFGILSRLAVLQLGNNNFTGEIPPELGKCTTLVWLDLNTNHLTGEIPPRLGRQPGSKALSGLLSGNTMAFVRNVGNSCKGVGGLVEFSGIRPERLLQIPSLKSCDFTRMYSGPILSLFTRYQTIEYLDLSYNQLRGKIPDEIGEMIALQVLELSHNQLSGEIPFTIGQLKNLGVFDASDNRLQGQIPESFSNLSFLVQIDLSNNELTGPIPQRGQLSTLPATQYANNPGLCGVPLPECKNGNNQLPAGTEEGKRAKHGTRAASWANSIVLGVLISAASVCILIVWAIAVRARRRDADDAKMLHSLQAVNSATTWKIEKEKEPLSINVATFQRQLRKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKLIRLSCQGDREFMAEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQYGSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLHHNCIPHIIHRDMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGDTNLVGWSKMKAREGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLRELRGSENNSHSHSNSL | ||||||
Glycosylation | 84 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 118 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 163 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 188 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 226 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 234 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 288 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 312 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 412 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 469 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 506 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 681 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Modified residue | 835 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 911 | Phosphotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 1001 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 1009 | Phosphotyrosine | ||||
Sequence: Y |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Expressed in provascular and procambial sites throughout plant development. Expressed throughout globe- to heart-staged embryos. Then, it is restricted to procambial cells by the late torpedo stage, and this pattern persists throughout the duration of embryo development. After germination, it is expressed not only in procambial cells throughout the plant but also in all lateral organ primordia before the onset of vascularization.
Gene expression databases
Interaction
Subunit
Interacts with TTL3.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q9ZPS9 | At1g17230 Q9SHI2 | 4 | EBI-2292728, EBI-20651261 | |
BINARY | Q9ZPS9 | At1g51790 A0A178WLG7 | 3 | EBI-2292728, EBI-20652336 | |
BINARY | Q9ZPS9 | BAM3 O65440-2 | 2 | EBI-2292728, EBI-20653325 | |
BINARY | Q9ZPS9 | RGI1 Q9LHP4 | 4 | EBI-2292728, EBI-20660903 | |
BINARY | Q9ZPS9 | TTL3 Q9SIN1 | 2 | EBI-2292728, EBI-2292882 | |
BINARY | Q9ZPS9 | VIK Q9XI87 | 2 | EBI-2292728, EBI-2292778 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for motif, repeat, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 68-75 | Cys pair 1 | ||||
Sequence: CQFSGVTC | ||||||
Repeat | 77-101 | LRR 1 | ||||
Sequence: GGRVTEINLSGSGLSGIVSFNAFTS | ||||||
Repeat | 102-125 | LRR 2 | ||||
Sequence: LDSLSVLKLSENFFVLNSTSLLLL | ||||||
Repeat | 126-150 | LRR 3 | ||||
Sequence: PLTLTHLELSSSGLIGTLPENFFSK | ||||||
Repeat | 151-175 | LRR 4 | ||||
Sequence: YSNLISITLSYNNFTGKLPNDLFLS | ||||||
Repeat | 177-200 | LRR 5 | ||||
Sequence: KKLQTLDLSYNNITGPISGLTIPL | ||||||
Repeat | 203-227 | LRR 6 | ||||
Sequence: CVSMTYLDFSGNSISGYISDSLINC | ||||||
Repeat | 228-250 | LRR 7 | ||||
Sequence: TNLKSLNLSYNNFDGQIPKSFGE | ||||||
Repeat | 251-275 | LRR 8 | ||||
Sequence: LKLLQSLDLSHNRLTGWIPPEIGDT | ||||||
Repeat | 277-299 | LRR 9 | ||||
Sequence: RSLQNLRLSYNNFTGVIPESLSS | ||||||
Repeat | 300-324 | LRR 10 | ||||
Sequence: CSWLQSLDLSNNNISGPFPNTILRS | ||||||
Repeat | 326-349 | LRR 11 | ||||
Sequence: GSLQILLLSNNLISGDFPTSISAC | ||||||
Repeat | 351-373 | LRR 12 | ||||
Sequence: SLRIADFSSNRFSGVIPPDLCPG | ||||||
Repeat | 374-398 | LRR 13 | ||||
Sequence: AASLEELRLPDNLVTGEIPPAISQC | ||||||
Repeat | 399-422 | LRR 14 | ||||
Sequence: SELRTIDLSLNYLNGTIPPEIGNL | ||||||
Repeat | 424-446 | LRR 15 | ||||
Sequence: KLEQFIAWYNNIAGEIPPEIGKL | ||||||
Repeat | 447-470 | LRR 16 | ||||
Sequence: QNLKDLILNNNQLTGEIPPEFFNC | ||||||
Repeat | 472-493 | LRR 17 | ||||
Sequence: NIEWVSFTSNRLTGEVPKDFGI | ||||||
Repeat | 494-518 | LRR 18 | ||||
Sequence: LSRLAVLQLGNNNFTGEIPPELGKC | ||||||
Repeat | 520-542 | LRR 19 | ||||
Sequence: TLVWLDLNTNHLTGEIPPRLGRQ | ||||||
Repeat | 570-594 | LRR 20 | ||||
Sequence: VGGLVEFSGIRPERLLQIPSLKSCD | ||||||
Repeat | 610-634 | LRR 21 | ||||
Sequence: YQTIEYLDLSYNQLRGKIPDEIGEM | ||||||
Repeat | 635-660 | LRR 22 | ||||
Sequence: IALQVLELSHNQLSGEIPFTIGQLKN | ||||||
Repeat | 662-681 | LRR 23 | ||||
Sequence: GVFDASDNRLQGQIPESFSN | ||||||
Repeat | 682-707 | LRR 24 | ||||
Sequence: LSFLVQIDLSNNELTGPIPQRGQLST | ||||||
Motif | 720-727 | Cys pair 2 | ||||
Sequence: CGVPLPEC | ||||||
Domain | 838-1129 | Protein kinase | ||||
Sequence: FSAASMIGHGGFGEVFKATLKDGSSVAIKKLIRLSCQGDREFMAEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQYGSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLHHNCIPHIIHRDMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGDTNLVGWSKMKAREGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLREL |
Domain
Contains two pairs of conservatively spaced Cys (Cys pair 1 and 2) possibly involved in forming some heterodimers.
Sequence similarities
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length1,143
- Mass (Da)125,676
- Last updated1999-05-01 v1
- Checksum7D1C88493F27A94E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC006532 EMBL· GenBank· DDBJ | AAD20088.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC05526.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY074313 EMBL· GenBank· DDBJ | AAL67010.1 EMBL· GenBank· DDBJ | mRNA |