Q9ZH79 · TONB_PASMU
- ProteinProtein TonB
- GenetonB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids256 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | outer membrane-bounded periplasmic space | |
Cellular Component | plasma membrane | |
Molecular Function | energy transducer activity | |
Biological Process | protein transport | |
Biological Process | siderophore transport | |
Biological Process | transmembrane transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameProtein TonB
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pasteurellales > Pasteurellaceae > Pasteurella
Accessions
- Primary accessionQ9ZH79
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Single-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-8 | Cytoplasmic | ||||
Sequence: MIDKSRSC | ||||||
Transmembrane | 9-29 | Helical; Signal-anchor | ||||
Sequence: IGFAISLLFHASFVSFLYWIV | ||||||
Topological domain | 30-256 | Periplasmic | ||||
Sequence: QKDDDSANGFAADIISTHISMEMLAATVLEEPEPEPEPAPPVVEPELPKEEVADPTVKPEPPKEPEKPKEPEKPKEKPKEKPKEKPKKPKKEQRDLPKSDRQIDSNSSINQQATTTGNITTNNPNLVGKGNSTDEVNAYRSALRREIEKHKRYPNRARMMRKQGVVTITFHLNNAGVISNARISKSSGSEELDNAALVAVNNARPIGPLPAGMPNEVSVPVSFRITN |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000196206 | 1-256 | Protein TonB | |||
Sequence: MIDKSRSCIGFAISLLFHASFVSFLYWIVQKDDDSANGFAADIISTHISMEMLAATVLEEPEPEPEPAPPVVEPELPKEEVADPTVKPEPPKEPEKPKEPEKPKEKPKEKPKEKPKKPKKEQRDLPKSDRQIDSNSSINQQATTTGNITTNNPNLVGKGNSTDEVNAYRSALRREIEKHKRYPNRARMMRKQGVVTITFHLNNAGVISNARISKSSGSEELDNAALVAVNNARPIGPLPAGMPNEVSVPVSFRITN |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 59-162 | Disordered | ||||
Sequence: EEPEPEPEPAPPVVEPELPKEEVADPTVKPEPPKEPEKPKEPEKPKEKPKEKPKEKPKKPKKEQRDLPKSDRQIDSNSSINQQATTTGNITTNNPNLVGKGNST | ||||||
Compositional bias | 76-130 | Basic and acidic residues | ||||
Sequence: LPKEEVADPTVKPEPPKEPEKPKEPEKPKEKPKEKPKEKPKKPKKEQRDLPKSDR | ||||||
Compositional bias | 131-162 | Polar residues | ||||
Sequence: QIDSNSSINQQATTTGNITTNNPNLVGKGNST | ||||||
Domain | 167-256 | TonB C-terminal | ||||
Sequence: AYRSALRREIEKHKRYPNRARMMRKQGVVTITFHLNNAGVISNARISKSSGSEELDNAALVAVNNARPIGPLPAGMPNEVSVPVSFRITN |
Sequence similarities
Belongs to the TonB family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length256
- Mass (Da)28,306
- Last updated1999-05-01 v1
- ChecksumFEF0D4E73577D193
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 76-130 | Basic and acidic residues | ||||
Sequence: LPKEEVADPTVKPEPPKEPEKPKEPEKPKEKPKEKPKEKPKKPKKEQRDLPKSDR | ||||||
Compositional bias | 131-162 | Polar residues | ||||
Sequence: QIDSNSSINQQATTTGNITTNNPNLVGKGNST |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF070473 EMBL· GenBank· DDBJ | AAC83227.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE004439 EMBL· GenBank· DDBJ | AAK03272.1 EMBL· GenBank· DDBJ | Genomic DNA |