Q9ZGM4 · KATG1_LEGPN

  • Protein
    Catalase-peroxidase 1
  • Gene
    katG1
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site95Transition state stabilizer
Active site99Proton acceptor
Binding site264Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase 1
  • EC number
  • Short names
    CP 1
  • Alternative names
    • Peroxidase/catalase 1

Gene names

    • Name
      katG1
    • Synonyms
      katB

Organism names

  • Taxonomic identifier
  • Strain
    • JR32
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Legionellales > Legionellaceae > Legionella

Accessions

  • Primary accession
    Q9ZGM4

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, cross-link.

Type
IDPosition(s)Description
ChainPRO_00003548151-721Catalase-peroxidase 1
Cross-link98↔223Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-249)
Cross-link223↔249Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-98)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Expression

Induction

Induced during exponential growth.

Interaction

Subunit

Homodimer or homotetramer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    721
  • Mass (Da)
    80,500
  • Last updated
    1999-05-01 v1
  • Checksum
    D96347BDAD0B719C
MDGKVGSTTTGCPVIHGGMTSTGTSNTAWWPNALNLDILHQHDTKTNPMEKDFNYREEVKKLDFEALKKDLHALMTDSQAWWPADWGHYGGLMIRMSWHAAGSYRVADGRGGAGTGNQRFAPLNSWPDNVNLDKARRLLWPIKKKYGNKISWADLIVLAGTIAYESMGLKTFGFGFGREDIWHPEKDVYWGSEQEWLGAKRYDGKSRESLENPLAAVQMGLIYVNPEGVNGQPDPLRTAQDVRVTFGRMAMNDEETVALTAGGHTVGKCHGNGNAKLLGPNPEAANVEDQGLGWINKTTRGIGRNTVSSGIEGAWTTHPTQWDNGYFYLLLNYDWELKKSPAGAWQWEPIHIKEEDKPVDVEDPAIRHNPIMTDADMAMKMDPVYRKIAERFYQDPDYFAEVFARAWFKLTHRDMGPKTRYIGPDVPKEDLIWQDPVPAGNRAYDIAAAKAKIAASNLTIGEMVSTAWDSARTFRGSDKRGGANGARIRLKPQKDWEGNEPQRLTKVLQILEDIATDTGASVADVIILAGNVGIEKAAKAAGFDIIVPFAPGRGDATDDMTDAESFDVLEPLHDGYRNWLKKTYDVRPEELMLDRTQLMGLTAHEMTVLVGGLRVLGTNHNNTQYGVFTDRVGALTNDFFVNLTDMANVWIPSKDNLYEIRDRKAGNIKWTATRVDLVFGSNSILRSYAEVYAQDDNKGKFIQDFVAAWTKVMNADRFDLA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF078110
EMBL· GenBank· DDBJ
AAC64361.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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