Q9ZAA8 · GCDD_ACIFV
- ProteinGlutaconyl-CoA decarboxylase subunit delta
- GenegcdD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids107 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Part of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). Possible membrane anchor for the alpha subunit.
Catalytic activity
- (2E)-glutaconyl-CoA + H+ + Na+(in) = (2E)-butenoyl-CoA + CO2 + Na+(out)
CHEBI:57353 + CHEBI:15378 + Na+ (in)CHEBI:29101= CHEBI:57332 + CHEBI:16526 + Na+ (out)CHEBI:29101
Pathway
Amino-acid degradation; L-glutamate degradation via hydroxyglutarate pathway; crotonoyl-CoA from L-glutamate: step 5/5.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | glutaconyl-CoA decarboxylase activity | |
Molecular Function | sodium ion transmembrane transporter activity | |
Biological Process | glutamate catabolic process via 2-hydroxyglutarate | |
Biological Process | sodium ion export across plasma membrane |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameGlutaconyl-CoA decarboxylase subunit delta
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Negativicutes > Acidaminococcales > Acidaminococcaceae > Acidaminococcus
Accessions
- Primary accessionQ9ZAA8
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 10-32 | Helical | ||||
Sequence: MINMTIVFGVLIVLGILMVLIHA |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000216466 | 1-107 | Glutaconyl-CoA decarboxylase subunit delta | |||
Sequence: MTDNPWLIMMINMTIVFGVLIVLGILMVLIHAVDPTKKVQGKKKPVVAKPAPSAAASKRQEEEKVAAMAAVLALVQDEDDMIAAALSAAIAEHKRKMEPMNLPHHSF |
Interaction
Subunit
Heterooctamer consisting of two alpha, two beta, two gamma and two delta subunits.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length107
- Mass (Da)11,624
- Last updated1999-05-01 v1
- Checksum7B363CF48D435C82
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF030576 EMBL· GenBank· DDBJ | AAC69171.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP001859 EMBL· GenBank· DDBJ | ADB48190.1 EMBL· GenBank· DDBJ | Genomic DNA |