Q9Y818 · UBC15_SCHPO

Function

function

Catalyzes the covalent attachment of ubiquitin to other proteins. Has a role in the formation of chromatin structures that influence the localization of transcriptional silencing factors.

Catalytic activity

  • S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.
    EC:2.3.2.23 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

Features

Showing features for active site.

116720406080100120140160
TypeIDPosition(s)Description
Active site90Glycyl thioester intermediate

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functionubiquitin conjugating enzyme activity
Biological Processproteasome-mediated ubiquitin-dependent protein catabolic process
Biological Processprotein polyubiquitination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ubiquitin-conjugating enzyme E2 15
  • EC number
  • Alternative names
    • E2 ubiquitin-conjugating enzyme 15
    • Ubiquitin carrier protein 15
    • Ubiquitin-protein ligase 15

Gene names

    • Name
      ubc15
    • ORF names
      SPBC1105.09

Organism names

Accessions

  • Primary accession
    Q9Y818

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000825891-167Ubiquitin-conjugating enzyme E2 15

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-165UBC core

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    167
  • Mass (Da)
    19,106
  • Last updated
    1999-11-01 v1
  • Checksum
    2289FD04069E1707
MPSSASEQLLRKQLKEIQKNPPQGFSVGLVDDKSIFEWEVMIIGPEDTLYEGGFFHATLSFPQDYPLMPPKMKFTTEIWHPNVHPNGEVCISILHPPGDDKYGYEDAGERWLPVHSPETILISVISMLSSPNDESPANIDAAKEFRENPQEFKKRVRRLVRRSIEMI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU329671
EMBL· GenBank· DDBJ
CAB50972.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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