crystal structures of SART3 in the apo-form and in complex with the DUSP-UBL domain of USP15 at 2.0 and 3.0 A respectively. Structural analysis reveals SART3 contains 12 half-a-tetratricopeptide (HAT) repeats organized into two subdomains HAT-N and HAT-C. SART3 dimerizes through the concave surface of HAT-C whereas the HAT-C convex surface binds USP15 in a novel bipartite mode.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.