Q9XI87 · VIK_ARATH
- ProteinSerine/threonine-protein kinase VIK
- GeneVIK
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids438 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Serine/threonine protein kinase which may function as an adapter protein for BRL2 (PubMed:19000166).
Required during vascular development for the establishment of vein pattern in foliar organs (PubMed:19000166).
Mediates MSSP1/TMT1 phosphorylation and activation to enhance its carrier activity and consequently vacuolar sugar accumulation, particularly in response to cold (PubMed:21838775).
Required during vascular development for the establishment of vein pattern in foliar organs (PubMed:19000166).
Mediates MSSP1/TMT1 phosphorylation and activation to enhance its carrier activity and consequently vacuolar sugar accumulation, particularly in response to cold (PubMed:21838775).
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Cellular Component | plant-type vacuole | |
Molecular Function | ATP binding | |
Molecular Function | MAP kinase kinase kinase activity | |
Molecular Function | protein serine/threonine/tyrosine kinase activity | |
Biological Process | auxin-activated signaling pathway | |
Biological Process | brassinosteroid mediated signaling pathway | |
Biological Process | cellular response to glucose stimulus | |
Biological Process | leaf vascular tissue pattern formation | |
Biological Process | positive regulation of glucose transmembrane transport | |
Biological Process | response to auxin | |
Biological Process | response to salt |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase VIK
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9XI87
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
Reduced sensitivity to auxin (e.g. 2,4-D and NPA) and brassinosteroids (BRs) associated with altered vein pattern in foliar organs (PubMed:19000166).
Decreased vacuolar sugar import associated with reduced fresh weight when grown on high glucose containing medium or in response to cold stress (PubMed:21838775).
Altered intracellular sugar compartmentation due to altered regulation of MSSP1/TMT1 (PubMed:21838775).
Decreased vacuolar sugar import associated with reduced fresh weight when grown on high glucose containing medium or in response to cold stress (PubMed:21838775).
Altered intracellular sugar compartmentation due to altered regulation of MSSP1/TMT1 (PubMed:21838775).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 10 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000456810 | 1-438 | Serine/threonine-protein kinase VIK | |||
Sequence: MSSDSPAAGDGGEQAAAGTSVPSPSYDKQKEKARVSRTSLILWHAHQNDAAAVRKLLEEDPTLVHARDYDKRTPLHVASLHGWIDVVKCLLEFGADVNAQDRWKNTPLADAEGARKQKMIELLKSHGGLSYGQNGSHFEPKPVPPPIPKKCDWEIEPAELDFSNAAMIGKGSFGEIVKAYWRGTPVAVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHQYLKEKGGLTPTTAVNFALDIARGMTYLHNEPNVIIHRDLKPRNVLLVNSSADHLKVGDFGLSKLIKVQNSHDVYKMTGETGSYRYMAPEVFKHRRYDKKVDVFSFAMILYEMLEGEPPFANHEPYEAAKHVSDGHRPTFRSKGCTPDLRELIVKCWDADMNQRPSFLDILKRLEKIKETLPSDHHWGLFTS |
Post-translational modification
Phosphorylated.
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Restricted to mature vascular cells (PubMed:19000166).
Mostly expressed in mature leaves and seeds, and, to a lower level, in seedlings, young leaves, flowers and siliques (PubMed:21838775).
Mostly expressed in mature leaves and seeds, and, to a lower level, in seedlings, young leaves, flowers and siliques (PubMed:21838775).
Induction
Induced by auxin (e.g. IAA) (PubMed:19000166).
Accumulates in response to salt (NaCl) (PubMed:21838775).
Accumulates in response to salt (NaCl) (PubMed:21838775).
Gene expression databases
Interaction
Subunit
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q9XI87 | BRL2 Q9ZPS9 | 2 | EBI-2292778, EBI-2292728 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, repeat, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-31 | Disordered | ||||
Sequence: MSSDSPAAGDGGEQAAAGTSVPSPSYDKQKE | ||||||
Repeat | 36-65 | ANK 1 | ||||
Sequence: SRTSLILWHAHQNDAAAVRKLLEEDPTLVH | ||||||
Repeat | 70-99 | ANK 2 | ||||
Sequence: DKRTPLHVASLHGWIDVVKCLLEFGADVNA | ||||||
Repeat | 103-133 | ANK 3 | ||||
Sequence: WKNTPLADAEGARKQKMIELLKSHGGLSYGQ | ||||||
Domain | 162-427 | Protein kinase | ||||
Sequence: FSNAAMIGKGSFGEIVKAYWRGTPVAVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHQYLKEKGGLTPTTAVNFALDIARGMTYLHNEPNVIIHRDLKPRNVLLVNSSADHLKVGDFGLSKLIKVQNSHDVYKMTGETGSYRYMAPEVFKHRRYDKKVDVFSFAMILYEMLEGEPPFANHEPYEAAKHVSDGHRPTFRSKGCTPDLRELIVKCWDADMNQRPSFLDILKRLEKIKETL |
Sequence similarities
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length438
- Mass (Da)49,335
- Last updated1999-11-01 v1
- ChecksumC61F80724E24BBD2
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 17 | in Ref. 3; AAL77660 | ||||
Sequence: A → V |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC007576 EMBL· GenBank· DDBJ | AAD39286.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AC068197 EMBL· GenBank· DDBJ | AAF79405.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002684 EMBL· GenBank· DDBJ | AEE29097.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY075653 EMBL· GenBank· DDBJ | AAL77660.1 EMBL· GenBank· DDBJ | mRNA | ||
BT026491 EMBL· GenBank· DDBJ | ABH04598.1 EMBL· GenBank· DDBJ | mRNA | ||
AK220869 EMBL· GenBank· DDBJ | BAD94246.1 EMBL· GenBank· DDBJ | mRNA |