Q9XI07 · SWI3C_ARATH
- ProteinSWI/SNF complex subunit SWI3C
- GeneSWI3C
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids807 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 345 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 348 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 368 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 371 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | SWI/SNF complex | |
Molecular Function | DNA binding | |
Molecular Function | zinc ion binding | |
Biological Process | chromatin remodeling |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameSWI/SNF complex subunit SWI3C
- Short namesAtSWI3C
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9XI07
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
Plants are viable but have alterations in leaf, root and flower development, and are early flowering.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 50 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000344529 | 1-807 | SWI/SNF complex subunit SWI3C | ||
Proteomic databases
PTM databases
Expression
Tissue specificity
Expressed in roots, stems, leaves, flowers and siliques.
Gene expression databases
Interaction
Subunit
Heterodimer. Interacts with SWI3A, SWI3B and BRM, but not with BSH. Interacts with MORC6 and SUVH9 (PubMed:27171427).
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | IntAct | |
---|---|---|---|---|---|
BINARY | Q9XI07 | SWI3B Q84JG2 | 4 | EBI-1102300, EBI-1102271 |
Complex viewer
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, zinc finger, coiled coil.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-74 | Disordered | |||
Compositional bias | 30-53 | Acidic residues | |||
Domain | 176-274 | SWIRM | |||
Zinc finger | 340-394 | ZZ-type; degenerate | |||
Domain | 398-449 | SANT | |||
Compositional bias | 458-484 | Polar residues | |||
Region | 458-487 | Disordered | |||
Region | 549-571 | Disordered | |||
Coiled coil | 598-656 | ||||
Region | 692-713 | Disordered | |||
Region | 721-740 | Disordered | |||
Region | 781-807 | Disordered | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length807
- Mass (Da)88,250
- Last updated1999-11-01 v1
- ChecksumDAB17C104E4B287F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 30-53 | Acidic residues | |||
Compositional bias | 458-484 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC007727 EMBL· GenBank· DDBJ | AAD41423.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE30144.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY091026 EMBL· GenBank· DDBJ | AAM13847.1 EMBL· GenBank· DDBJ | mRNA | ||
AY117245 EMBL· GenBank· DDBJ | AAM51320.1 EMBL· GenBank· DDBJ | mRNA |