Q9X755 · KEFF_KLEAE
- ProteinGlutathione-regulated potassium-efflux system ancillary protein KefF
- GenekefF
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids177 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
Catalytic activity
- a quinone + NADH + H+ = a quinol + NAD+
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 8 | FMN (UniProtKB | ChEBI) | |||
Binding site | 14-17 | FMN (UniProtKB | ChEBI) | |||
Binding site | 65-68 | FMN (UniProtKB | ChEBI) | |||
Binding site | 105-108 | FMN (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | electron transfer activity | |
Molecular Function | FMN binding | |
Molecular Function | NADH:ubiquinone reductase (non-electrogenic) activity | |
Molecular Function | NADPH dehydrogenase (quinone) activity | |
Biological Process | positive regulation of ion transmembrane transporter activity | |
Biological Process | positive regulation of potassium ion transmembrane transport | |
Biological Process | potassium ion transport |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameGlutathione-regulated potassium-efflux system ancillary protein KefF
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella
Accessions
- Primary accessionQ9X755
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000071638 | 1-177 | Glutathione-regulated potassium-efflux system ancillary protein KefF | ||
Interaction
Structure
Family & Domains
Sequence similarities
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length177
- Mass (Da)20,161
- Last updated1999-11-01 v1
- Checksum2D6457C4BBDD7D39
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ242913 EMBL· GenBank· DDBJ | CAB44436.1 EMBL· GenBank· DDBJ | Genomic DNA |