Q9WYJ4 · MDS_THEMA

Function

function

Catalyzes the transfer of the mannosyl group from GDP-mannose to di-myo-inositol-1,3'-phosphate (DIP), producing mannosyl-di-myo-inositol phosphate (MDIP). Can also use MDIP as an acceptor of a second mannose residue, yielding di-mannosyl-di-myo-inositol phosphate (MMDIP). Minor amounts of the tri-mannosylated form are also formed.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Mg2+ is required for maximal activity.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
16 mMDIP
0.7 mMGDP-mannose

Temperature Dependence

Optimum temperature is 95 degrees Celsius.

GO annotations

AspectTerm
Molecular Functionglycosyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    GDP-mannose:di-myo-inositol-1,3'-phosphate beta-1,2-mannosyltransferase
  • EC number
  • Alternative names
    • MDIP synthase

Gene names

    • Name
      mds
    • ORF names
      Tmari_0357
    • Ordered locus names
      TM_0359

Organism names

Accessions

  • Primary accession
    Q9WYJ4
  • Secondary accessions
    • G4FHS1
    • R4NYA7

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004498211-356GDP-mannose:di-myo-inositol-1,3'-phosphate beta-1,2-mannosyltransferase

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the MDIP synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    356
  • Mass (Da)
    41,972
  • Last updated
    1999-11-01 v1
  • Checksum
    58B3A66B38ECDC98
MKIGFLSRWGATCGVGMHAEILAREFIRMGHEVVVFAPTEESASKEVKYYKRTEAQDPEFVKREIYTEVDNVTEEGWVKEEEILKENLDLLIIETFWRVPVKPLTRLIEKLKIPVISVFHEANIFKAREVVKLPCDKIVVFDRRFYDEILEFYEIPREKVEVISYPVMKPYDAEPERPVSEDKFLFFSFGRQPVEEYCDFLNALKKLRKRFDNVHYWIIRSDGRVDYEAEWITQWQKRPTVEKLYSYLKGSNVHLLPKGNTPNVVVSSTLYQIIASETPIVIRDSRFVETIETDVYGFGPIVKYRNIHDLVHKLELLMLDRELVEDIKKEVRVFVEKYGGDKIAQEFLDLAKTITK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE000512
EMBL· GenBank· DDBJ
AAD35446.1
EMBL· GenBank· DDBJ
Genomic DNA
CP004077
EMBL· GenBank· DDBJ
AGL49282.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp