Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse.Biggs W.H. III, Cavenee W.K., Arden K.C.View abstractCited forNUCLEOTIDE SEQUENCECategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCMamm. Genome 12:416-425 (2001)Cited in23Mapped to68
Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells.McKimpson W.M., Spiegel S., Mukhanova M., Kraakman M., Du W., Kitamoto T., Yu J., Deng Z., Pajvani U., Accili D.View abstractAnnotationCalorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells.SourceGeneRif: 56458PubMedEurope PMCJ Cell Biol 223:e202305093-e202305093 (2024)Mapped to5
Inhibitory Regulation of FOXO1 in PPARdelta Expression Drives Mitochondrial Dysfunction and Insulin Resistance.Park S., Cha H.N., Shin M.G., Park S., Kim Y., Kim M.S., Shin K.H., Thoudam T., Lee E.J.[...], Park S.Y.View abstractAnnotationInhibitory Regulation of FOXO1 in PPARdelta Expression Drives Mitochondrial Dysfunction and Insulin Resistance.SourceGeneRif: 56458PubMedEurope PMCDiabetes 73:1084-1098 (2024)Mapped to8
hnRNPU is required for spermatogonial stem cell pool establishment in mice.Wen Y., Zhou S., Gui Y., Li Z., Yin L., Xu W., Feng S., Ma X., Gan S.[...], Yuan S.View abstractCategoriesFunctionSourceMGI: 1890077PubMedEurope PMCCell Rep 43:114113-114113 (2024)Mapped to54
FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury.Zhou M., Liu Y.W., He Y.H., Zhang J.Y., Guo H., Wang H., Ren J.K., Su Y.X., Yang T.[...], Dai S.S.View abstractAnnotationFOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury.CategoriesFunctionSourceGeneRif: 56458PubMedEurope PMCMil Med Res 11:20-20 (2024)Mapped to5
Sirt1 alleviates osteoarthritis via promoting FoxO1 nucleo-cytoplasm shuttling to facilitate autophagy.Xu M., Qian Z., Zhang Y., Gao X., Ma Z., Jin X., Wu S.View abstractAnnotationSirt1 alleviates osteoarthritis via promoting FoxO1 nucleo-cytoplasm shuttling to facilitate autophagy.CategoriesExpressionSourceGeneRif: 56458PubMedEurope PMCInt Immunopharmacol 131:111893-111893 (2024)Mapped to5
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.Shi L., Yang J., Tao Z., Zheng L., Bui T.F., Alonso R.L., Yue F., Cheng Z.View abstractAnnotationLoss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.CategoriesFunctionSourceGeneRif: 56458PubMedEurope PMCClin Sci (Lond) 138:371-385 (2024)Mapped to5
Type 1 interferons and Foxo1 down-regulation play a key role in age- related T-cell exhaustion in mice.Durand A., Bonilla N., Level T., Ginestet Z., Lombes A., Guichard V., Germain M., Jacques S., Letourneur F.[...], Lucas B.View abstractAnnotationType 1 interferons and Foxo1 down-regulation play a key role in age-related T-cell exhaustion in mice.CategoriesPTM / Processing, InteractionSourceGeneRif: 56458, MGI: 1890077PubMedEurope PMCNat Commun 15:1718-1718 (2024)Mapped to5
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractCategoriesFunctionSourceMGI: 1890077PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Transcription factor FoxO1 regulates myoepithelial cell diversity and growth.Tokumasu R., Yasuhara R., Kang S., Funatsu T., Mishima K.View abstractAnnotationTranscription factor FoxO1 regulates myoepithelial cell diversity and growth.CategoriesFunctionSourceGeneRif: 56458, MGI: 1890077PubMedEurope PMCSci Rep 14:1069-1069 (2024)Mapped to19
FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy.van der Weijden V.A., Stotzel M., Iyer D.P., Fauler B., Gralinska E., Shahraz M., Meierhofer D., Vingron M., Rulands S.[...], Bulut-Karslioglu A.View abstractAnnotationFOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy.CategoriesFunctionSourceGeneRif: 56458PubMedEurope PMCNat Cell Biol 26:181-193 (2024)Mapped to5
Downregulation of Sirt3 contributes to beta-cell dedifferentiation via FoxO1 in type 2 diabetic mellitus.Nie Y., Zhang Y., Liu S., Xu Z., Xia C., Du L., Yin X., Wang J.View abstractAnnotationDownregulation of Sirt3 contributes to beta-cell dedifferentiation via FoxO1 in type 2 diabetic mellitus.CategoriesFunctionSourceGeneRif: 56458PubMedEurope PMCActa Diabetol 61:485-494 (2024)Mapped to7
TOX3 deficiency mitigates hyperglycemia by suppressing hepatic gluconeogenesis through FoxO1.Liu C., Zheng Y., Hu S., Liang X., Li Y., Yu Z., Liu Y., Bian Y., Man Y.[...], Zhang Y.View abstractSourceMGI: 1890077PubMedEurope PMCMetabolism 152:155766-155766 (2024)Mapped to19
Thrombospondin-1 promotes liver fibrosis by enhancing TGF-beta action in hepatic stellate cells.Imamori M., Hosooka T., Imi Y., Hosokawa Y., Yamaguchi K., Itoh Y., Ogawa W.View abstractCategoriesFunctionSourceMGI: 1890077PubMedEurope PMCBiochem Biophys Res Commun 693:149369-149369 (2024)Mapped to29
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors.Searcy M.B., Larsen R.K., Stevens B.T., Zhang Y., Jin H., Drummond C.J., Langdon C.G., Gadek K.E., Vuong K.[...], Hatley M.E.View abstractAnnotationPAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors.CategoriesFunctionSourceGeneRif: 56458, MGI: 1890077PubMedEurope PMCNat Commun 14:7291-7291 (2023)Mapped to18
FOXO1 reduces STAT3 activation and causes impaired mitochondrial quality control in diabetic cardiomyopathy.Zhou L., Su W., Wang Y., Zhang Y., Xia Z., Lei S.View abstractAnnotationFOXO1 reduces STAT3 activation and causes impaired mitochondrial quality control in diabetic cardiomyopathy.CategoriesFunction, SequencesSourceGeneRif: 56458PubMedEurope PMCDiabetes Obes Metab 26:732-744 (2024)Mapped to14
Decreased FoxO1 expression contributes to facet joint osteoarthritis pathogenesis by impairing chondrocyte migration and extracellular matrix synthesis.Chen C., Xu G., Chen J., Wu C., Zhang J., Jiang J., Hong H., Cui Z.View abstractAnnotationDecreased FoxO1 expression contributes to facet joint osteoarthritis pathogenesis by impairing chondrocyte migration and extracellular matrix synthesis.CategoriesFunctionSourceGeneRif: 56458PubMedEurope PMCCell Signal 113:110942-110942 (2024)Mapped to5
PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.Kim K.H., Oprescu S.N., Snyder M.M., Kim A., Jia Z., Yue F., Kuang S.View abstractAnnotationPRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.CategoriesSequencesSourceGeneRif: 56458, MGI: 1890077PubMedEurope PMCCell Rep 42:113329-113329 (2023)Mapped to39
Oocyte quality is impaired in a hyperandrogenic PCOS mouse model by increased Foxo1 expression.Danfeng D., Ke D., Dengxuan F., Xuelian L., Congjian X.View abstractAnnotationOocyte quality is impaired in a hyperandrogenic PCOS mouse model by increased Foxo1 expression.CategoriesFunctionSourceGeneRif: 56458PubMedEurope PMCReprod Biol 23:100812-100812 (2023)Mapped to5
eNOS Regulates Lymphatic Valve Specification by Controlling beta-Catenin Signaling During Embryogenesis in Mice.Iyer D., Mastrogiacomo D.M., Li K., Banerjee R., Yang Y., Scallan J.P.View abstractCategoriesFunctionSourceMGI: 1890077PubMedEurope PMCArterioscler Thromb Vasc Biol 43:2197-2212 (2023)Mapped to23
Hepatocyte FoxO1 Deficiency Protects From Liver Fibrosis via Reducing Inflammation and TGF-beta1-mediated HSC Activation.Pan Q., Gao M., Kim D., Ai W., Yang W., Jiang W., Brashear W., Dai Y., Li S.[...], Guo S.View abstractAnnotationHepatocyte FoxO1 Deficiency Protects From Liver Fibrosis via Reducing Inflammation and TGF-beta1-mediated HSC Activation.CategoriesFunctionSourceGeneRif: 56458PubMedEurope PMCCell Mol Gastroenterol Hepatol 17:41-58 (2024)Mapped to24
Suppression of FOXO1 attenuates inflamm-aging and improves liver function during aging.Yang W., Kim D.M., Jiang W., Ai W., Pan Q., Rahman S., Cai J.J., Brashear W.A., Sun Y., Guo S.View abstractAnnotationSuppression of FOXO1 attenuates inflamm-aging and improves liver function during aging.CategoriesSequences, Phenotypes & VariantsSourceGeneRif: 56458PubMedEurope PMCAging Cell 22:e13968-e13968 (2023)Mapped to5
FOXO 1 deletion in chondrocytes rescues diabetes-impaired fracture healing by restoring angiogenesis and reducing apoptosis.Alharbi M.A., Graves D.T.View abstractAnnotationFOXO 1 deletion in chondrocytes rescues diabetes-impaired fracture healing by restoring angiogenesis and reducing apoptosis.CategoriesFunctionSourceGeneRif: 56458PubMedEurope PMCFront Endocrinol (Lausanne) 14:1136117-1136117 (2023)Mapped to5
TRIM28 modulates nuclear receptor signaling to regulate uterine function.Li R., Wang T., Marquardt R.M., Lydon J.P., Wu S.P., DeMayo F.J.View abstractCategoriesFunctionSourceMGI: 1890077PubMedEurope PMCNat Commun 14:4605-4605 (2023)Mapped to99+
Vaccine adjuvant-elicited CD8pisup>+pi/sup> T cell immunity is co- dependent on T-bet and FOXO1.Ivanova D.L., Thompson S.B., Klarquist J., Harbell M.G., Kilgore A.M., Lasda E.L., Hesselberth J.R., Hunter C.A., Kedl R.M.View abstractCategoriesFunctionSourceMGI: 1890077PubMedEurope PMCCell Rep 42:112911-112911 (2023)Mapped to13