Q9WVA4 · TAGL2_MOUSE
- ProteinTransgelin-2
- GeneTagln2
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids199 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | actin cytoskeleton | |
Molecular Function | actin filament binding | |
Biological Process | actin filament organization | |
Biological Process | epithelial cell differentiation |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTransgelin-2
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ9WVA4
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for initiator methionine, modified residue, chain, cross-link.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Initiator methionine | 1 | Removed | ||||
Sequence: M | ||||||
Modified residue | 2 | N-acetylalanine | ||||
Sequence: A | ||||||
Chain | PRO_0000204787 | 2-199 | Transgelin-2 | |||
Sequence: ANRGPSYGLSREVQQKIEKQYDADLEQILIQWITTQCREDVGQPQPGRENFQKWLKDGTVLCKLINSLYPEGQAPVKKIQASSMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL | ||||||
Modified residue | 11 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 17 | N6-acetyllysine | ||||
Sequence: K | ||||||
Modified residue | 20 | N6-acetyllysine | ||||
Sequence: K | ||||||
Modified residue | 163 | Phosphoserine | ||||
Sequence: S | ||||||
Cross-link | 171 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Modified residue | 180 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 182 | Omega-N-methylarginine | ||||
Sequence: R | ||||||
Modified residue | 196 | Omega-N-methylarginine | ||||
Sequence: R |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 24-136 | Calponin-homology (CH) | ||||
Sequence: ADLEQILIQWITTQCREDVGQPQPGRENFQKWLKDGTVLCKLINSLYPEGQAPVKKIQASSMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLA | ||||||
Repeat | 174-199 | Calponin-like | ||||
Sequence: IGLQMGTNRGASQAGMTGYGMPRQIL |
Sequence similarities
Belongs to the calponin family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length199
- Mass (Da)22,395
- Last updated2008-12-16 v4
- Checksum3CA18C829CA2CC99
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0A6YXG6 | A0A0A6YXG6_MOUSE | Tagln2 | 90 |
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 46 | in Ref. 4; BAE39928 | ||||
Sequence: Q → K | ||||||
Sequence conflict | 192-199 | in Ref. 2; AAD37787 | ||||
Sequence: YGMPRQIL → MGCHGDPLIILSLLPLPSMNG |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF465519 EMBL· GenBank· DDBJ | AAM54133.1 EMBL· GenBank· DDBJ | mRNA | ||
AF149291 EMBL· GenBank· DDBJ | AAD37787.1 EMBL· GenBank· DDBJ | mRNA | ||
AK172892 EMBL· GenBank· DDBJ | BAD32170.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
AK151576 EMBL· GenBank· DDBJ | BAE30516.1 EMBL· GenBank· DDBJ | mRNA | ||
AK167395 EMBL· GenBank· DDBJ | BAE39484.1 EMBL· GenBank· DDBJ | mRNA | ||
AK167922 EMBL· GenBank· DDBJ | BAE39928.1 EMBL· GenBank· DDBJ | mRNA | ||
AK171088 EMBL· GenBank· DDBJ | BAE42241.1 EMBL· GenBank· DDBJ | mRNA | ||
CH466520 EMBL· GenBank· DDBJ | EDL39010.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC009076 EMBL· GenBank· DDBJ | AAH09076.1 EMBL· GenBank· DDBJ | mRNA | ||
BC049861 EMBL· GenBank· DDBJ | AAH49861.1 EMBL· GenBank· DDBJ | mRNA |