NHE1, NHE2, and NHE3 contribute to regulation of intracellular pH in murine duodenal epithelial cells.Praetorius J., Andreasen D., Jensen B.L., Ainsworth M.A., Friis U.G., Johansen T.View abstractCited forNUCLEOTIDE SEQUENCEStrainC57 black/6CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCAm. J. Physiol. 278:G197-G206 (2000)Cited in12Mapped to11
Contributions of Na+/H+ exchanger isoforms to preimplantation development of the mouse.Barr K.J., Garrill A., Jones D.H., Orlowski J., Kidder G.M.View abstractCategoriesSequencesSourceMGI: 105075PubMedEurope PMCMol Reprod Dev 50:146-153 (1998)Mapped to14
Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion.Schultheis P.J., Clarke L.L., Meneton P., Harline M., Boivin G.P., Stemmermann G., Duffy J.J., Doetschman T., Miller M.L., Shull G.E.View abstractCategoriesFunctionSourceMGI: 105075PubMedEurope PMCJ. Clin. Invest. 101:1243-1253 (1998)Cited in1Mapped to5
Chromosomal assignment of four genes encoding Na/H exchanger isoforms in human and rat.Szpirer C., Szpirer J., Riviere M., Levan G., Orlowski J.View abstractCategoriesSequencesSourceMGI: 105075PubMedEurope PMCMamm Genome 5:153-159 (1994)Mapped to10
Sodium/hydrogen-exchanger-2 modulates colonocyte lineage differentiation.Nikolovska K., Cao L., Hensel I., Di Stefano G., Seidler A.E., Zhou K., Qian J., Singh A.K., Riederer B., Seidler U.View abstractCategoriesFunction, ExpressionSourceMGI: 105075PubMedEurope PMCActa Physiol. 234:e13774-e13774 (2022)Cited in1Mapped to2
In silico mapping of quantitative trait loci (QTL) regulating the milk ionome in mice identifies a milk iron locus on chromosome 1.Hadsell D.L., Hadsell L.A., Rijnkels M., Carcamo-Bahena Y., Wei J., Williamson P., Grusak M.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105075PubMedEurope PMCMamm Genome 29:632-655 (2018)Mapped to6
Bcl-x<sub>L</sub> deamidation is regulated by multiple ion transporters and is intramolecularly catalyzed.Dho S.H., Manson S.R., Jung S.H., Lim J.C., Weintraub S.J.View abstractCategoriesFunction, PTM / ProcessingSourceMGI: 105075PubMedEurope PMCBiochim Biophys Acta Mol Cell Res 1865:995-1001 (2018)Mapped to28
Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse.Shawki A., Engevik M.A., Kim R.S., Knight P.B., Baik R.A., Anthony S.R., Worrell R.T., Shull G.E., Mackenzie B.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105075PubMedEurope PMCAm J Physiol Gastrointest Liver Physiol 311:G423-30 (2016)Mapped to6
The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine.Xia W., Yu Q., Riederer B., Singh A.K., Engelhardt R., Yeruva S., Song P., Tian D.A., Soleiman M., Seidler U.View abstractCategoriesFunctionSourceMGI: 105075PubMedEurope PMCPflugers Arch 466:1541-1556 (2014)Mapped to17
Molecular transport machinery involved in orchestrating luminal acid- induced duodenal bicarbonate secretion in vivo.Singh A.K., Liu Y., Riederer B., Engelhardt R., Thakur B.K., Soleimani M., Seidler U.View abstractCategoriesFunctionSourceMGI: 105075PubMedEurope PMCJ Physiol 591:5377-5391 (2013)Mapped to29
NHE1 is the sodium-hydrogen exchanger active in acute intracellular pH regulation in preimplantation mouse embryos.Siyanov V., Baltz J.M.View abstractCategoriesExpressionSourceMGI: 105075PubMedEurope PMCBiol Reprod 88:157-157 (2013)Mapped to26
Trefoil factor 2 requires Na/H exchanger 2 activity to enhance mouse gastric epithelial repair.Xue L., Aihara E., Wang T.C., Montrose M.H.View abstractCategoriesFunctionSourceMGI: 105075PubMedEurope PMCJ. Biol. Chem. 286:38375-38382 (2011)Cited in1Mapped to12
NHE2X3 DKO mice exhibit gender-specific NHE8 compensation.Xu H., Li J., Chen R., Zhang B., Wang C., King N., Chen H., Ghishan F.K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105075PubMedEurope PMCAm J Physiol Gastrointest Liver Physiol 300:G647-53 (2011)Mapped to9
Cftr and ENaC ion channels mediate NaCl absorption in the mouse submandibular gland.Catalan M.A., Nakamoto T., Gonzalez-Begne M., Camden J.M., Wall S.M., Clarke L.L., Melvin J.E.View abstractCategoriesSubcellular LocationSourceMGI: 105075PubMedEurope PMCJ Physiol 588:713-724 (2010)Mapped to23
Mice lacking the Na+/H+ exchanger 2 have impaired recovery of intestinal barrier function.Moeser A.J., Nighot P.K., Ryan K.A., Simpson J.E., Clarke L.L., Blikslager A.T.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 105075PubMedEurope PMCAm J Physiol Gastrointest Liver Physiol 295:G791-7 (2008)Mapped to3
Increased renal renin content in mice lacking the Na+/H+ exchanger NHE2.Hanner F., Chambrey R., Bourgeois S., Meer E., Mucsi I., Rosivall L., Shull G.E., Lorenz J.N., Eladari D., Peti-Peterdi J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105075PubMedEurope PMCAm J Physiol Renal Physiol 294:F937-44 (2008)Mapped to3
NHE10, an osteoclast-specific member of the Na+/H+ exchanger family, regulates osteoclast differentiation and survival [corrected].Lee S.H., Kim T., Park E.S., Yang S., Jeong D., Choi Y., Rho J.View abstractCategoriesSequencesSourceMGI: 105075PubMedEurope PMCBiochem. Biophys. Res. Commun. 369:320-326 (2008)Cited in1Mapped to7
Enhanced formation of a HCO3- transport metabolon in exocrine cells of Nhe1-/- mice.Gonzalez-Begne M., Nakamoto T., Nguyen H.V., Stewart A.K., Alper S.L., Melvin J.E.View abstractCategoriesFunctionSourceMGI: 105075PubMedEurope PMCJ Biol Chem 282:35125-35132 (2007)Mapped to23
Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain- sensitive alpha1 Na,K-ATPase.Lorenz J.N., Dostanic-Larson I., Shull G.E., Lingrel J.B.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105075PubMedEurope PMCJ Am Soc Nephrol 17:2457-2463 (2006)Mapped to18
NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na+-dependent acid extrusion mechanism is upregulated in NHE2-null mice.Guan Y., Dong J., Tackett L., Meyer J.W., Shull G.E., Montrose M.H.View abstractCategoriesFunctionSourceMGI: 105075PubMedEurope PMCAm. J. Physiol. 291:G689-G699 (2006)Cited in1Mapped to12
SLC26A9 is expressed in gastric surface epithelial cells, mediates Cl-/HCO3- exchange, and is inhibited by NH4+.Xu J., Henriksnas J., Barone S., Witte D., Shull G.E., Forte J.G., Holm L., Soleimani M.View abstractCategoriesFunction, ExpressionSourceMGI: 105075PubMedEurope PMCAm. J. Physiol. 289:C493-C505 (2005)Cited in2Mapped to6
NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice.Bailey M.A., Giebisch G., Abbiati T., Aronson P.S., Gawenis L.R., Shull G.E., Wang T.View abstractCategoriesFunctionSourceMGI: 105075PubMedEurope PMCJ Physiol 561:765-775 (2004)Mapped to6
The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation.Bachmann O., Riederer B., Rossmann H., Groos S., Schultheis P.J., Shull G.E., Gregor M., Manns M.P., Seidler U.View abstractCategoriesExpressionSourceMGI: 105075PubMedEurope PMCAm. J. Physiol. 287:G125-G133 (2004)Cited in1Mapped to12
Critical role for NHE1 in intracellular pH regulation in pancreatic acinar cells.Brown D.A., Melvin J.E., Yule D.I.View abstractCategoriesFunctionSourceMGI: 105075PubMedEurope PMCAm J Physiol Gastrointest Liver Physiol 285:G804-12 (2003)Mapped to13
The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+ -ATPase.Miller M.L., Judd L.M., Van Driel I.R., Andringa A., Flagella M., Bell S.M., Schultheis P.J., Spicer Z., Shull G.E.View abstractCategoriesFunction, Subcellular LocationSourceMGI: 105075PubMedEurope PMCCell Tissue Res 309:369-380 (2002)Mapped to19