Q9W495 · PGAP1_DROME

Function

function

Involved in inositol deacylation of GPI-anchored proteins.

Features

Showing features for active site.

1980100200300400500600700800900
TypeIDPosition(s)Description
Active site170

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentendoplasmic reticulum membrane
Molecular Functionphosphatidylinositol deacylase activity
Biological Processendoplasmic reticulum to Golgi vesicle-mediated transport
Biological ProcessGPI anchor metabolic process
Biological Processpositive regulation of ER to Golgi vesicle-mediated transport
Biological Processprotein transport

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    GPI inositol-deacylase
  • EC number
  • Alternative names
    • Post-GPI attachment to proteins factor 1

Gene names

    • Name
      PGAP1
    • ORF names
      CG3160

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9W495
  • Secondary accessions
    • Q8T8Q8

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-7Cytoplasmic
Transmembrane8-28Helical
Topological domain29-628Lumenal
Transmembrane629-649Helical
Topological domain650-709Cytoplasmic
Transmembrane710-730Helical
Topological domain731-774Lumenal
Transmembrane775-795Helical
Topological domain796-867Cytoplasmic
Transmembrane868-888Helical
Topological domain889-895Lumenal
Transmembrane896-916Helical
Topological domain917-929Cytoplasmic
Transmembrane930-950Helical
Topological domain951-954Lumenal
Transmembrane955-975Helical
Topological domain976-980Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation.

Type
IDPosition(s)Description
ChainPRO_00002776271-980GPI inositol-deacylase
Glycosylation427N-linked (GlcNAc...) asparagine
Glycosylation517N-linked (GlcNAc...) asparagine
Glycosylation596N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region821-853Disordered
Compositional bias833-853Basic and acidic residues

Sequence similarities

Belongs to the GPI inositol-deacylase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    980
  • Mass (Da)
    111,625
  • Last updated
    2002-10-01 v3
  • Checksum
    72EA24B3B68E18EF
MFMFRNCAVLLVIGSICCFIYGLFRLHVEVEPNACRMTYMFGEPMFAKVGVRDGDQYPNYALYYYYEGLRQPLDPLKRRMTGAPVIFVPGNAGSYKQVRSLASVALRKAMSNDAGIHLDYYTIDYDEELSALYGGYLHRQQSYLKLCIRTILSIYEGRTEQPSIVLIGHSMGGKLAQSVLVDPAIGQHINTIISISTPLDQPVLNLDTQLEEFYDQTDAVLSKLRTATVPTMTTNVCDSLHQRPPSVQRMASQDSSARLDNVLLISTGGGNRDLLVRPGLTSSRFNDLHAMTSAIPKVSLSCDHLSAVWCLQFMQAINRFLFSVAYVREDRSSIAFGTNKQRNLQTALSTFVKPRRRQQNTVRFGAAGNWHEERRLVINKYFTNGLKGTFFDLIGLQRQERYRKAAIEALNVDDEDWLFGCSAEDNNKTGQLYCEKATSLMHLVQWLPNEDREPRSIALLDLHNLRKTYVHWTHLLVRLPPSAKRIGYNLDIYDPKERVTDIKMPRWYTMAKLPLINETLQGTLHHRVRISEMVDPYQSIRVIVEPLQCINPEYRVTARICVPWAAGFERFQTLKSFDQKPQLYVNVPTLVPRHYNTTLNPVTLELYLDPTCRYRISYEYSYSSALSRLVLEFYGWLPAHLVCVLLIVLRKQVETFYDVGTFRSLRPYVGYLQYTSLYIVTACRLLKKLIISSRVFPEPEPLDYSINVSIVIHCAAIALSLLATLGTWLALTLYGNAFYRLALRITRLSQATSNVMISIMTHLPITYGILTIATAMGTCSGVGLLLAFVFYFLMLSNAYKDYLEDFLWQKAANLVRGKPSAVTEQEDATEEQNEEQNALKQNDEQKQQQQEEEEPEACVGLQNFSFHVTLLLMLFVQLLLNAPSSLAWLRSRRHGINLPDPSLYPSIVVLASLSLLLQLRAPQKCQGYWMLSIAFYILAGVVLLYCQAAIYRLTYVIAGAFALLSAHQSLWILWGRVSRV

Features

Showing features for sequence conflict, compositional bias.

Type
IDPosition(s)Description
Sequence conflict459in Ref. 3; AAL68379
Sequence conflict605in Ref. 3; AAL68379
Compositional bias833-853Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014298
EMBL· GenBank· DDBJ
AAF46062.3
EMBL· GenBank· DDBJ
Genomic DNA
AY075574
EMBL· GenBank· DDBJ
AAL68379.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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