Q9W0N9 · Q9W0N9_DROME
- ProteinEarthbound 1
- Geneebd1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids581 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Publications for Q9W0N9
Inter-Species Rescue of Mutant Phenotype-The Standard for Genetic Analysis of Human Genetic Disorders in <i>Drosophila melanogaster</i> Model.
- CategoriesNames, Function, Phenotypes & Variants
- SourceFlyBase: FBgn0035153
Histone lysine methyltransferase Pr-set7/SETD8 promotes neural stem cell reactivation.
- CategoryFunction
- SourceFlyBase: FBgn0035153
Wnt Signalling in Intestinal Stem Cells: Lessons from Mice and Flies.
- CategoryFunction
- SourceFlyBase: FBgn0035153
Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing.
- Annotationin the adult intestine Ebd acts independently of Ewg in physiological Wnt signaling but cooperates with Ewg to induce the hyperactivation of Wnt target gene expression following Apc1 loss. These findings have relevance for human tumorigenesis as Jerky (JRK/JH8) the human Ebd homolog promotes Wnt pathway hyperactivation and is overexpressed in colorectal breast and ovarian cancers
- CategoryFunction
- SourceFlyBase: FBgn0035153, GeneRif: 38082
mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster.
- CategorySequences
- SourceFlyBase: FBgn0035153
Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes.
- CategoriesFunction, Subcellular Location
- SourceFlyBase: FBgn0035153
SUMO-Enriched Proteome for Drosophila Innate Immune Response.
- CategoryPTM / Processing
- SourceFlyBase: FBgn0035153
The many landscapes of recombination in Drosophila melanogaster.
- CategorySequences
- SourceFlyBase: FBgn0035153
Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating beta-catenin-TCF activity.
- CategoriesFunction, Sequences
- SourceFlyBase: FBgn0035153, IntAct: Q9W0N9
A genome-wide Drosophila screen for heat nociception identifies alpha2delta3 as an evolutionarily conserved pain gene.
- CategoryPhenotypes & Variants
- SourceFlyBase: FBgn0035153
Systematic genetic analysis of muscle morphogenesis and function in Drosophila.
- CategoryFunction
- SourceFlyBase: FBgn0035153
The chromatin-remodeling protein Osa interacts with CyclinE in Drosophila eye imaginal discs.
- CategoriesFunction, Expression
- SourceFlyBase: FBgn0035153
A protein interaction map of Drosophila melanogaster.
- CategoryInteraction
- SourceIntAct: Q9W0N9