Q9VXN4 · SYRC_DROME
- ProteinProbable arginine--tRNA ligase, cytoplasmic
- GeneArgRS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids665 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
Catalytic activity
- tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 204-206 | L-arginine (UniProtKB | ChEBI) | |||
Binding site | 215 | L-arginine (UniProtKB | ChEBI) | |||
Binding site | 390 | L-arginine (UniProtKB | ChEBI) | |||
Binding site | 394 | L-arginine (UniProtKB | ChEBI) | |||
Binding site | 418 | L-arginine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | aminoacyl-tRNA synthetase multienzyme complex | |
Cellular Component | cytoplasm | |
Cellular Component | cytosol | |
Molecular Function | arginine-tRNA ligase activity | |
Molecular Function | ATP binding | |
Biological Process | arginyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable arginine--tRNA ligase, cytoplasmic
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ9VXN4
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000151662 | 1-665 | Probable arginine--tRNA ligase, cytoplasmic | ||
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for motif, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Motif | 205-216 | 'HIGH' region | |||
Region | 535-549 | Interaction with tRNA | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length665
- Mass (Da)75,577
- Last updated2000-05-01 v1
- MD5 ChecksumE5E47DC220F38C592CE0C80BE6021DFF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014298 EMBL· GenBank· DDBJ | AAF48524.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY070924 EMBL· GenBank· DDBJ | AAL48546.1 EMBL· GenBank· DDBJ | mRNA |