Q9VVU1 · Q9VVU1_DROME
- ProteinShort/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- GeneGH07925p
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids414 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- (2R)-2-methylbutanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = ethylacryloyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- (2S)-2-methylbutanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- 2-methylpropanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = (2E)-2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- H+ + hexanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- H+ + oxidized [electron-transfer flavoprotein] + valproyl-CoA = (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- butanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
Cofactor
Pathway
Amino-acid degradation; L-isoleucine degradation.
Lipid metabolism; mitochondrial fatty acid beta-oxidation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrion | |
Molecular Function | 2-methylbutanoyl-CoA dehydrogenase activity | |
Molecular Function | acyl-CoA dehydrogenase activity | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | short-chain fatty acyl-CoA dehydrogenase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameShort/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ9VVU1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 38-148 | Acyl-CoA dehydrogenase/oxidase N-terminal | ||||
Sequence: TDDEKMMKETVAKLAQEQIQPLVKKMDFEHKFDPSVVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKAKYLPKLAQ | ||||||
Domain | 153-248 | Acyl-CoA oxidase/dehydrogenase middle | ||||
Sequence: SFALTEPGAGSDAFSLKTVAKKDGSHYVINGSKMWISNSDVAGVFLIFANAKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNV | ||||||
Domain | 260-406 | Acyl-CoA dehydrogenase/oxidase C-terminal | ||||
Sequence: GHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLSTIAK |
Sequence similarities
Belongs to the acyl-CoA dehydrogenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length414
- Mass (Da)45,366
- Last updated2000-05-01 v1
- Checksum97736FBADD20E767
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014296 EMBL· GenBank· DDBJ | AAF49216.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT044429 EMBL· GenBank· DDBJ | ACH92494.1 EMBL· GenBank· DDBJ | mRNA |