Q9VSQ1 · Q9VSQ1_DROME
- ProteinFormin homology 2 domain containing, isoform A
- GeneFhos
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1393 (go to sequence)
- Protein existencePredicted
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytoskeleton | |
Cellular Component | nucleus | |
Cellular Component | perinuclear region of cytoplasm | |
Molecular Function | actin filament binding | |
Biological Process | cortical actin cytoskeleton organization | |
Biological Process | imaginal disc-derived wing morphogenesis | |
Biological Process | muscle cell cellular homeostasis | |
Biological Process | muscle system process | |
Biological Process | positive regulation of cell migration | |
Biological Process | positive regulation of stress fiber assembly | |
Biological Process | positive regulation of substrate adhesion-dependent cell spreading | |
Biological Process | programmed cell death involved in cell development | |
Biological Process | salivary gland histolysis | |
Biological Process | trachea morphogenesis | |
Biological Process | wound healing, spreading of cells |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ9VSQ1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Family & Domains
Features
Showing features for domain, region, compositional bias, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 56-419 | GBD/FH3 | ||||
Sequence: RLLNAPQSIDDAAIQVYKDGDYGAYLDLESSLAEQAEEIEGVNVSRKNSLVVRTQLNVRVQAIIEKLLSAQGSDLRRALFSLKQVFQEDKDLVHAFVALGGLNCLVRVGNCADQNYQNYILRALGQVMLYVDGMNGVMKHEPTMQWLYSLIASNYRSVVKTALKLLLVFVEYAESNCYVLVSAIHAVDASQGTLPWSNIMRLLKDYDNADAELVIYATSLINKTLAGLNDQDSFYDESDLLEQQGMETVIQRYMSKPGTDLDLLDQLQLYEAVLKFEDGESDGQRLPQNSMRKTQRYRPGANTTERRKSRRHSTDNSPASLTKVLPTTVLRMTPTQATVDEDSSGSTNSTEFSGGLFNEKKPRD | ||||||
Region | 335-378 | Disordered | ||||
Sequence: ESDGQRLPQNSMRKTQRYRPGANTTERRKSRRHSTDNSPASLTK | ||||||
Compositional bias | 338-353 | Polar residues | ||||
Sequence: GQRLPQNSMRKTQRYR | ||||||
Compositional bias | 354-369 | Basic and acidic residues | ||||
Sequence: PGANTTERRKSRRHST | ||||||
Compositional bias | 391-410 | Polar residues | ||||
Sequence: QATVDEDSSGSTNSTEFSGG | ||||||
Region | 391-431 | Disordered | ||||
Sequence: QATVDEDSSGSTNSTEFSGGLFNEKKPRDGAGVTPGLRRRR | ||||||
Coiled coil | 566-593 | |||||
Sequence: INGIMKNIQQTDSAYKKYENEANRLNNY | ||||||
Region | 624-709 | Disordered | ||||
Sequence: GFDFTPAPLSSTPVKCDVPPEPEPLSPVKKPAAAPPPPPPPPPPPPPPPGWWHAPIYNSPQARTLTSTNPELLPHPVDPSDMESED | ||||||
Compositional bias | 636-677 | Pro residues | ||||
Sequence: PVKCDVPPEPEPLSPVKKPAAAPPPPPPPPPPPPPPPGWWHA | ||||||
Compositional bias | 682-696 | Polar residues | ||||
Sequence: SPQARTLTSTNPELL | ||||||
Region | 757-788 | Disordered | ||||
Sequence: KEGLAKSKSKGEISRSSSVDQDVKKSEPKKSE | ||||||
Compositional bias | 759-788 | Basic and acidic residues | ||||
Sequence: GLAKSKSKGEISRSSSVDQDVKKSEPKKSE | ||||||
Domain | 883-1274 | FH2 | ||||
Sequence: GNNTIKKNKKTVKLFWKEVREDMIPQVVGKTIWDELPDANVDTQKLEHLFESRAKDLMTKKQQELNKSKEIIVLDHKRSNAINIAITKLPPPRAIKTAILKMDATVVTREGIDKLLNMLPTDEERGKIQEAQLSNPELPLGSAEQFLLTLASISELEARLKLWAFRLDFDNSEKEIAEPLMDLKQGIEILRQNRTFRSILSTLLSVGIFLNGAPVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMESSSDTSDLYSEIGPITRASKADFTDLAHNLNQLEAECKACWDRLKLIAKHDCPPPLKQKLVDFLADCAERIIILQIVHRRVMNRYRKFLLWLGMPQHSVAESRPNEFCRTLSEFALEYRTTRERVQQQLEKKANHRERNKTRGK | ||||||
Domain | 1332-1364 | DAD | ||||
Sequence: TDGDDEILESLVKTATKAPGTRTTPRERKRTRH | ||||||
Region | 1343-1379 | Disordered | ||||
Sequence: VKTATKAPGTRTTPRERKRTRHADRKSLRRTLKNGLT |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,393
- Mass (Da)155,853
- Last updated2002-10-01 v2
- ChecksumFE9A50B953B680F8
Computationally mapped potential isoform sequences
There are 7 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 338-353 | Polar residues | ||||
Sequence: GQRLPQNSMRKTQRYR | ||||||
Compositional bias | 354-369 | Basic and acidic residues | ||||
Sequence: PGANTTERRKSRRHST | ||||||
Compositional bias | 391-410 | Polar residues | ||||
Sequence: QATVDEDSSGSTNSTEFSGG | ||||||
Compositional bias | 636-677 | Pro residues | ||||
Sequence: PVKCDVPPEPEPLSPVKKPAAAPPPPPPPPPPPPPPPGWWHA | ||||||
Compositional bias | 682-696 | Polar residues | ||||
Sequence: SPQARTLTSTNPELL | ||||||
Compositional bias | 759-788 | Basic and acidic residues | ||||
Sequence: GLAKSKSKGEISRSSSVDQDVKKSEPKKSE |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014296 EMBL· GenBank· DDBJ | AAF50365.2 EMBL· GenBank· DDBJ | Genomic DNA |