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Q9VKJ0 · HGD_DROME

Function

Catalytic activity

Cofactor

Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Pathway

Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.

Features

Showing features for binding site.

143950100150200250300350400
TypeIDPosition(s)Description
Binding site335Fe cation (UniProtKB | ChEBI)
Binding site341Fe cation (UniProtKB | ChEBI)
Binding site371Fe cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionhomogentisate 1,2-dioxygenase activity
Molecular Functionmetal ion binding
Biological ProcessL-phenylalanine catabolic process
Biological Processtyrosine catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Homogentisate 1,2-dioxygenase
  • EC number
  • Alternative names
    • Homogentisate oxygenase
    • Homogentisic acid oxidase
    • Homogentisicase

Gene names

    • Name
      Hgo
    • ORF names
      CG4779

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9VKJ0
  • Secondary accessions
    • Q86P40

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002202421-439Homogentisate 1,2-dioxygenase

Proteomic databases

Expression

Gene expression databases

    • FBgn0040211Expressed in capitellum (Drosophila) and 11 other cell types or tissues

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the homogentisate dioxygenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    439
  • Mass (Da)
    49,398
  • Last updated
    2003-07-25 v3
  • MD5 Checksum
    C794BF621B9C0F2B4A9980828F7B2C9A
MSEYKYLSGFGSHFSSEDERYPNSLPVGQNSPQVCPYKLYAEQLSGSAFTAPRTENMRTWLYRKLPSAAHLPFQPFKGAEYFSQNWDEQPPNPNQLRWKPFDLPPKDGKNVNFVEGLHTVCGAGDPRSRHGLAIHIYSCNGSMDNSAFYNSDGDFLIVPQQGVLDITTEFGRMSVAPNEICVIPQGIRFAVNVDSPSRGYILEVYDDHFVLPDLGPIGANGLANPRDFETPVAWFDDRDVKDFQVISKFQGRLFVAKQNHTVFDVVAWHGNYVPFKYDLSKFMVINSVSFDHCDPSIFTVLTCPSLRAGTAIADFVIFPPRWSVQEHTFRPPYYHRNCMSEFMGLILGKYEAKEDGFAAGGATLHSMMTPHGPDVKCFEGASNAKLVPERVAEGTQAFMFESSLSLAVTKWGEETCQKLDAAYYECWQALKNNFQITKN

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict96-106in Ref. 1; AAF36489

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF131124
EMBL· GenBank· DDBJ
AAF36489.1
EMBL· GenBank· DDBJ
Genomic DNA
AE014134
EMBL· GenBank· DDBJ
AAF53078.2
EMBL· GenBank· DDBJ
Genomic DNA
BT003496
EMBL· GenBank· DDBJ
AAO39500.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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