Q9VK41 · TTC30_DROME

Function

function

Required for polyglutamylation of axonemal tubulin in sensory cilia. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxonemal microtubule
Cellular Componentcilium
Cellular Componentintraciliary transport particle B
Molecular Functionintraciliary transport particle B binding
Biological Processcilium assembly
Biological Processintraciliary transport
Biological Processprotein polyglutamylation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Tetratricopeptide repeat protein 30 homolog
  • Short names
    TPR repeat protein 30 homolog

Gene names

    • Name
      Ttc30
    • ORF names
      CG5142

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9VK41
  • Secondary accessions
    • Q4V562
    • Q4V594

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003332131-655Tetratricopeptide repeat protein 30 homolog

Proteomic databases

Expression

Gene expression databases

Interaction

Complex viewer

View interactors in UniProtKB
View CPX-2704 in Complex Portal

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for repeat.

TypeIDPosition(s)Description
Repeat10-43TPR 1
Repeat44-76TPR 2
Repeat143-176TPR 3
Repeat178-210TPR 4
Repeat385-418TPR 5
Repeat450-484TPR 6
Repeat534-567TPR 7

Sequence similarities

Belongs to the TTC30/dfy-1/fleer family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    655
  • Mass (Da)
    73,046
  • Last updated
    2012-05-16 v3
  • Checksum
    78716129432977E6
MLHQGIILREGHVTRTIYNLIKDKRYEDVIECITSFGEAANTRAGLSTLGHCYYHAQKYEEAATCYEQLCQLAPKEAKYRFYYAQSLYQAGIFADALRVLKQMGDQEDELREQCLQLQSAILYSSEDFAGAQSLLNQRAGGTADTLNDEGCLLFQADQHEAAVQRFQAALQVGGFNPLVAYNVALAHFQKKQRAQALDYTSEIVERGMRNHPELGIGAQMDIPDGGARSVGNPITMAISGITQALNLKAAIEFQDGNEEAARDALLDLPPRAESELDPVTLHNMALTDVEGPVAGLRKLAFLLELGAPSCPKETFANILLICCKNELYETAADILAEHTDLTYKYLSQYLYELLDSLITAQTSAELAEKKLGTLASSLAGKLRSLAAKVQEVRATNEQQALRDALKDYEQALELYLPVVMARAWISWRDDDFVGAEREFHASAEFCSENSIWRLNAGHVLFMQGDKYNEAAAFYEPIVRQHSDDIMSVSAAVLANLCVSYIMTFQNEEAEELMRKVEKAEEMKGNLGKQYHHLCIVNLVVGTLYCAKSNYEFGLSRIAHALESGSGNRLYADTWLHVKHCILGLLTGMAKQNIILPYATVQEVLNFLRFCESYGLFTPANIFSATEQVPEEPLTIGLEARKLRLLLIKLSEYDNF

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
M9PDD5M9PDD5_DROMETtc30655

Sequence caution

The sequence AAY55178.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence AAY55187.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence AAY55210.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence AAY55218.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict47in Ref. 3; AAY55178
Sequence conflict579in Ref. 3; AAY55178/AAY55187/AAY55210/AAY55218

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014134
EMBL· GenBank· DDBJ
AAF53241.3
EMBL· GenBank· DDBJ
Genomic DNA
BT022762
EMBL· GenBank· DDBJ
AAY55178.1
EMBL· GenBank· DDBJ
mRNA Different initiation
BT022771
EMBL· GenBank· DDBJ
AAY55187.1
EMBL· GenBank· DDBJ
mRNA Different initiation
BT022794
EMBL· GenBank· DDBJ
AAY55210.1
EMBL· GenBank· DDBJ
mRNA Different initiation
BT022802
EMBL· GenBank· DDBJ
AAY55218.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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