Q9VK41 · TTC30_DROME
- ProteinTetratricopeptide repeat protein 30 homolog
- GeneTtc30
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids655 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Required for polyglutamylation of axonemal tubulin in sensory cilia. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | axonemal microtubule | |
Cellular Component | cilium | |
Cellular Component | intraciliary transport particle B | |
Molecular Function | intraciliary transport particle B binding | |
Biological Process | cilium assembly | |
Biological Process | intraciliary transport | |
Biological Process | protein polyglutamylation |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameTetratricopeptide repeat protein 30 homolog
- Short namesTPR repeat protein 30 homolog
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ9VK41
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000333213 | 1-655 | Tetratricopeptide repeat protein 30 homolog | ||
Proteomic databases
Expression
Gene expression databases
Interaction
Complex viewer
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for repeat.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Repeat | 10-43 | TPR 1 | |||
Repeat | 44-76 | TPR 2 | |||
Repeat | 143-176 | TPR 3 | |||
Repeat | 178-210 | TPR 4 | |||
Repeat | 385-418 | TPR 5 | |||
Repeat | 450-484 | TPR 6 | |||
Repeat | 534-567 | TPR 7 | |||
Sequence similarities
Belongs to the TTC30/dfy-1/fleer family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length655
- Mass (Da)73,046
- Last updated2012-05-16 v3
- Checksum78716129432977E6
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
M9PDD5 | M9PDD5_DROME | Ttc30 | 655 |
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 47 | in Ref. 3; AAY55178 | |||
Sequence conflict | 579 | in Ref. 3; AAY55178/AAY55187/AAY55210/AAY55218 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014134 EMBL· GenBank· DDBJ | AAF53241.3 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT022762 EMBL· GenBank· DDBJ | AAY55178.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
BT022771 EMBL· GenBank· DDBJ | AAY55187.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
BT022794 EMBL· GenBank· DDBJ | AAY55210.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
BT022802 EMBL· GenBank· DDBJ | AAY55218.1 EMBL· GenBank· DDBJ | mRNA | Different initiation |