Q9VH01 · Q9VH01_DROME
- ProteinBIR repeat containing ubiquitin-conjugating enzyme, isoform A
- GeneBruce
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids4876 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | cysteine-type endopeptidase inhibitor activity | |
Molecular Function | ubiquitin conjugating enzyme activity | |
Biological Process | apoptotic process | |
Biological Process | cellular response to starvation | |
Biological Process | negative regulation of apoptotic process | |
Biological Process | negative regulation of macroautophagy | |
Biological Process | negative regulation of nurse cell apoptotic process | |
Biological Process | oogenesis | |
Biological Process | programmed cell death | |
Biological Process | protein polyubiquitination | |
Biological Process | regulation of cytokinesis | |
Biological Process | ubiquitin-dependent protein catabolic process |
Keywords
- Molecular function
- Biological process
Protein family/group databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ9VH01
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q9VH01 | klhl10 Q6GKZ1 | 2 | EBI-2509194, EBI-15659303 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, coiled coil, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 502-527 | Disordered | ||||
Sequence: SESSTSVSNDSGSVSSGGGQLMKSSS | ||||||
Region | 645-666 | Disordered | ||||
Sequence: HQNNNNNNNNNNEASSLGGNSS | ||||||
Coiled coil | 1558-1626 | |||||
Sequence: KEKGEEMLNDLVNDVECLVEEMKVDENEKQEKVDYDAFGLVNGFKDKTLSSLNSVKQTLKEEVKKEKAD | ||||||
Region | 2238-2300 | Disordered | ||||
Sequence: STKSKGAGPTKSTSTGGKINMGSSGLCVGGPSSSSGNTSKSAASSSSPKNQAVPGTDGERDSN | ||||||
Compositional bias | 2242-2294 | Polar residues | ||||
Sequence: KGAGPTKSTSTGGKINMGSSGLCVGGPSSSSGNTSKSAASSSSPKNQAVPGTD | ||||||
Region | 2874-2904 | Disordered | ||||
Sequence: RQPSEVTIPEEEELSNQSQTDETKAEQLNTE | ||||||
Compositional bias | 2882-2898 | Polar residues | ||||
Sequence: PEEEELSNQSQTDETKA | ||||||
Region | 3851-3870 | Disordered | ||||
Sequence: RAGETSASSSGVSSATAKSS | ||||||
Compositional bias | 4202-4248 | Polar residues | ||||
Sequence: GAPISEPSPSGTSSGSGTIGNGSGNGSVSGTKTNAPEEATPSATSDD | ||||||
Region | 4202-4257 | Disordered | ||||
Sequence: GAPISEPSPSGTSSGSGTIGNGSGNGSVSGTKTNAPEEATPSATSDDKSHMYWAKG | ||||||
Domain | 4532-4699 | UBC core | ||||
Sequence: SRVKRLAQEAVTLSTSLPLSFSSSVFVRCDTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDYPNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWNAQTSSFLQVLVSIQSLILVPEPYFNEPGFERSRGSPSGTNSSREYNSNIYQACVRWAM | ||||||
Region | 4829-4857 | Disordered | ||||
Sequence: CEADGDAEGDGEVDDGFKGFPQEEGLLTG |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length4,876
- Mass (Da)539,214
- Last updated2004-07-05 v3
- ChecksumDD858A2584BB3A73
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0B4KG50 | A0A0B4KG50_DROME | Bruce | 4976 | ||
A0A0B4KFQ0 | A0A0B4KFQ0_DROME | Bruce | 4865 | ||
A0A0B4KGR9 | A0A0B4KGR9_DROME | Bruce | 4875 | ||
A0A0B4KH36 | A0A0B4KH36_DROME | Bruce | 4852 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 2242-2294 | Polar residues | ||||
Sequence: KGAGPTKSTSTGGKINMGSSGLCVGGPSSSSGNTSKSAASSSSPKNQAVPGTD | ||||||
Compositional bias | 2882-2898 | Polar residues | ||||
Sequence: PEEEELSNQSQTDETKA | ||||||
Compositional bias | 4202-4248 | Polar residues | ||||
Sequence: GAPISEPSPSGTSSGSGTIGNGSGNGSVSGTKTNAPEEATPSATSDD |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014297 EMBL· GenBank· DDBJ | AAF54520.3 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF517634 EMBL· GenBank· DDBJ | AAM77747.1 EMBL· GenBank· DDBJ | mRNA |