Q9VG55 · HUGIN_DROME
- ProteinProtein hugin
- GeneHug
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids191 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Probably has a role in larval molting.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Cellular Component | extracellular space | |
Molecular Function | ecdysis-triggering hormone activity | |
Molecular Function | hormone activity | |
Molecular Function | myostimulatory hormone activity | |
Molecular Function | neuropeptide receptor binding | |
Molecular Function | signaling receptor binding | |
Biological Process | ecdysis, chitin-based cuticle | |
Biological Process | larval feeding behavior | |
Biological Process | neuropeptide signaling pathway |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameProtein hugin
- Cleaved into 3 chains
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ9VG55
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for propeptide, signal, peptide, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Propeptide | PRO_0000029911 | ?-171 | ||||
Sequence: MCGPSYCTLLLIAASCYILVCSHAKSLQGTSKLDLGNHISAGSARGSLSPASPALSEARQKRAMGDYKELTDIIDELEENSLAQKASATMQVAAMPPQGQEFDLDTMPPLTYYLLLQKLRQLQSNGEPAYRVRTPRLGRSIDSWRLLDAEGATGMAGGEEAIGGQFMQRMV | ||||||
Signal | 1-24 | |||||
Sequence: MCGPSYCTLLLIAASCYILVCSHA | ||||||
Propeptide | PRO_0000029908 | 25-119 | ||||
Sequence: KSLQGTSKLDLGNHISAGSARGSLSPASPALSEARQKRAMGDYKELTDIIDELEENSLAQKASATMQVAAMPPQGQEFDLDTMPPLTYYLLLQKL | ||||||
Peptide | PRO_0000029909 | 121-137 | Hug-gamma | |||
Sequence: QLQSNGEPAYRVRTPRL | ||||||
Modified residue | 137 | Leucine amide | ||||
Sequence: L | ||||||
Peptide | PRO_0000029910 | 140-? | Hug-peptide | |||
Sequence: MCGPSYCTLLLIAASCYILVCSHAKSLQGTSKLDLGNHISAGSARGSLSPASPALSEARQKRAMGDYKELTDIIDELEENSLAQKASATMQVAAMPPQGQEFDLDTMPPLTYYLLLQKLRQLQSNGEPAYRVRTPRLGR | ||||||
Peptide | PRO_0000029912 | 174-181 | PK-2 | |||
Sequence: SVPFKPRL | ||||||
Modified residue | 181 | Leucine amide | ||||
Sequence: L | ||||||
Propeptide | PRO_0000029913 | 185-191 | ||||
Sequence: AQVCGGD |
Keywords
- PTM
Proteomic databases
Expression
Tissue specificity
Expressed in a subgroup of neurosecretory cells in the subesophageal ganglion from embryonic stage 9 to larval stages.
Developmental stage
Expressed during embryogenesis through to adult stages with highest expression at later half of embryogenesis and during larval stages.
Gene expression databases
Structure
Family & Domains
Sequence similarities
Belongs to the pyrokinin family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length191
- Mass (Da)20,623
- Last updated2000-05-01 v1
- Checksum78F4A9811C57D932
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ133105 EMBL· GenBank· DDBJ | CAB88005.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE014297 EMBL· GenBank· DDBJ | AAF54833.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY047528 EMBL· GenBank· DDBJ | AAK77260.1 EMBL· GenBank· DDBJ | mRNA |