Q9VFC4 · Q9VFC4_DROME

Function

Catalytic activity

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.
    EC:2.3.2.27 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentsperm flagellum
Cellular Componentubiquitin ligase complex
Molecular Functionubiquitin protein ligase activity
Molecular Functionubiquitin-protein transferase activity
Molecular Functionzinc ion binding
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RING-type E3 ubiquitin transferase
  • EC number

Gene names

    • Name
      Kpc1
    • Synonyms
      Dmel\CG6752
    • ORF names
      CG6752
      , Dmel_CG6752

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9VFC4

Proteomes

Organism-specific databases

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q9VFC4Kpc2 Q86LF03EBI-32711491, EBI-182816
View interactors in UniProtKB
View CPX-2708 in Complex Portal

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain74-253B30.2/SPRY
Domain1265-1303RING-type

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,332
  • Mass (Da)
    151,046
  • Last updated
    2000-05-01 v1
  • Checksum
    7DE1B95205EBFD60
MSISKLFVKVFNEDIFEQVDHDNLYSDLDDDLEGANCSTVPDPRPAKLADLSVTKQMLIVRTWLDDKFQQIQTDSNEEIRRLYMETESRIGPDLTIFDVDYTTTVRVSSDRLALRSQGSFNTVRANCCVYGGRWMYEIHLHTKGVMQIGWASNSCQFNENSGVGDTKSSYGYDGSKQQIWHISTKKYGDKWQIGDVIGVTIDVDKEVIEYYRNGRSMGVAFNKLEKGPGISFFAAISLGYTQGIEANFGNRPFMYPVSGFQPLMARPILKLQRANLLMNYLVNLAGIFSKYNAQSGMAPTNGADARVSTKKTVYCIFATLLIEKFTNEIFDPYIIEDVLLRKISSMTNLASEKENSYSVLHGLLSLFWNYMEGDEIKFVLRKLVNALLGTFTHTIQGLDYEKHRQALGMLHCLCLHEQTRKYLLEGKLFKKHCLAFFLYIHPLEFYIMEELLPDSMAWTEGIDGPKEKYLNVVEKVRKVTEPLYTAQKDLLCTLMINSDGSRESPSSRSIFLSKLRRYVIDLSMEQRPFHAFFFMQSSIQHPLDAPVALAFASILIDQTRSMFKDEMPTKNVEVNSDYFIDGTFDYMHFDRVGGVLSHLRKVHRGDIDARLGSARTQQIYEDDRQNLRVNEVDTTLYLLGENINNVPVVGHTQGANNTTYTHFLNTRPNSSTDSSPGNADMEASLCELLDLCIIFYYSAGHKYIVKIATVRDEIAALNEVLKETKFYREDIERKLGALEQHANVCMNENHQHVMGELRSKFSQRQNVFATRSIALARKQVWLRGVALNNHRRSLLIWLLERMLRTLTTASNTGSLFSFVPEVYVNTLPILLDAVMDFSHHDLKAQFEASDAECSVNAAAEFLGIHSADPRIVLASCKDSLLQALGTLTCHKSGVRALERTSKRSQASLVRALLRPYENRAWGQSNWLLLRFWMGEGYAYKDSRQPSVWQGGSLPLHQGLCRSRSRNETHTGLLHNVAPANPSKHFQRLIGAKLLEDEPFATAFLNSVLSQLNWAFSEFILLLQEIQNTAQRQENTLFEPKQLKICSMCFELTVSLMRCLEMVITTAPEIVTDESRPNSDLLLNRICQLISQVLSRVTVPPGCFQFVVDMCSADLNAVTHYPIVTAALGILLALMQEEMESDLRPQIVTRVSRAFLTDPSFQFATLEFALGEIRTPLLEQKNIPRGNFDPSSRPHIDPLTNDVRVPLPNNSKRIRADPPILKFALNDFPSHVSSEEIDNVRRLIDSLRVKQTLLSDITLPSEDSLCPICCAKPITAVFTPCKHQSCSDCIMQHMMNSKVCFYCKTTIQTIETLDGTVIFSNDDVVQTPMIERA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014297
EMBL· GenBank· DDBJ
AAF55136.1
EMBL· GenBank· DDBJ
Genomic DNA
BT031171
EMBL· GenBank· DDBJ
ABY20412.1
EMBL· GenBank· DDBJ
mRNA
AE014297
EMBL· GenBank· DDBJ
AFH06434.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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