Q9VF51 · Q9VF51_DROME

Function

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

Mo-molybdopterin (UniProtKB | Rhea| CHEBI:71302 )

Note: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 2 [2Fe-2S] clusters.

Features

Showing features for binding site, active site.

112541002003004005006007008009001,0001,1001,200
TypeIDPosition(s)Description
Binding site42[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site47[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site50[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site66[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site106[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site109[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site142[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site144[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site369FAD (UniProtKB | ChEBI)
Binding site388FAD (UniProtKB | ChEBI)
Binding site729Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site875Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site1027Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Active site1198Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentperoxisome
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Functionaldehyde oxidase activity
Molecular FunctionFAD binding
Molecular Functioniron ion binding
Molecular Functionoxidoreductase activity
Biological Processacetaldehyde metabolic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Aldehyde oxidase 3, isoform A
    • Aldehyde oxidase 3, isoform B
      (EC:1.2.3.1
      )
    • FI04488p

Gene names

    • Name
      AOX3
    • Synonyms
      CG6045-RA
      , DmAO3
      , Dmel\CG6045
    • ORF names
      CG6045
      , Dmel_CG6045

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9VF51

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain197-379FAD-binding PCMH-type

Sequence similarities

Belongs to the xanthine dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,254
  • Mass (Da)
    137,887
  • Last updated
    2000-05-01 v1
  • Checksum
    4CC7F24F15D80851
MTTKFSINGLPYAVNLTNLPPDITLNTFIREHAQLTATKFMCQEGGCGACICVVRDGKRSWAVNSCLTLLNTCAQLEIVTAEGLGNQRTGYNPIQKRLAKMNGTQCGFCSPGFVMNMYGLMEQNEGKVTMAEVENSFGGNICRCTGYRPILDAMKSFAVDSNIAIPAECGDIEDLKPRNCPKTGQACSGSCLPSTLVYEDGVQWHWPKSLSELFDALDKVKDSEEFMLVAGNTAHGVYRRSTDIKHFIDVQGVEELHQHSSEGQQLKLGANLSLTQTMEIIRTTSKQPGFEYLDVLWNHIDLIANVPVRNSGTLAGNISIKKQNPEFPSDIFISFEALNVKVVALKNAADEKEMSLAEYLGTNDKKLVLKTFVLPAYPKDKYIYESYKIMPRAQNAHAYVNAAFLLELEADNKVKSARICFGGIRPDFIHASAIEKLLVGQNPYESSLVEQTFTKLEDLIKPDEVLPDASPAYRSKLACGLFYKFLLKHAPVAEVGEKFRSGGQILQRPLSSGLQVFQTQKKNYPVTQAVEKVEGMIQCSGEATYMNDVLTTSNTLHCAFVGATKVGSTIDSIDASEALKQPGVIAFYSAKDIPGTNTFCEPSFGFEVEEIFCSGLVRHSEQPAGVIVALTADQAHRAAKLVRISYSNPSSDFKLQPSLGDVFASPTPDSSRIVPASKSTSKKIKFSEQPDKEVRGIFQMGLQYHFTMEPQTTVAIPFEDGLKIFSATQWMDQTQSVIAHMLQVKAKDVQLQVRRLGGGYGSKITRGNQVACAASLVAYKLNRPVRFVQSLESMMDCNGKRWACRSDYKCHIKDNGKIVGLTNDFYEDAGWSPNESPIEGHSTFTAVNCYDLNGDNFKNNGNAVLTDAPSSTWCRAPGSVEGIAMIENIIEHVAFEVQKDPAEVRLANIAAGNKISELLPQFLESREYAQRKKEIESHNAKNRWTKRGLGLAVMDYPIFYFGQYPATVAIYHVDGTVVVTHGGIEMGQGMNTKVAQVAAYTLGIDLSFIKVESSDTINGANSMVTGGAVGSESLCYAVRKACETLNSRLEPVKKKDASWIETVEAAYGKSINLIASDHYKKGDMQNYHIYGLALTEVELDVLTGNSQIKRVDILEDAGESLSPWIDIGQIEGAFVMCLGYWMSEQLVYDRETGRLLTNRTWNYKPPGAKDIPIDFRIELIQKPNPSGAGFMRSKATGEPPCCLAVSVVFALRQALDSARHDAGLPREWVRLGAPTTPETLVVNAGHEAASFRLK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014297
EMBL· GenBank· DDBJ
AAF55209.1
EMBL· GenBank· DDBJ
Genomic DNA
BT044575
EMBL· GenBank· DDBJ
ACI16537.1
EMBL· GenBank· DDBJ
mRNA
AE014297
EMBL· GenBank· DDBJ
ALI30573.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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