Q9VF20 · Q9VF20_DROME

Function

Catalytic activity

  • heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:7.6.2.5 (UniProtKB | ENZYME | Rhea)
  • pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentearly endosome membrane
Cellular Componentextracellular region
Cellular ComponentGolgi membrane
Cellular Componentlysosomal membrane
Cellular Componentmelanosome membrane
Cellular Componentmitochondrial outer membrane
Cellular Componentmultivesicular body membrane
Cellular Componentvacuolar membrane
Molecular FunctionABC-type heme transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionheme binding
Biological Processcellular detoxification of cadmium ion
Biological Processheme transport
Biological Processtransmembrane transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-binding cassette sub-family B member 6
  • EC number
  • Alternative names
    • ABC-type heme transporter ABCB6

Gene names

    • Name
      Hmt-1
    • Synonyms
      ABCB6
      , DmCG4225
      , Dmel\CG4225
      , EP(3)3387
      , HMT-1
      , hmt-1
    • ORF names
      CG4225
      , Dmel_CG4225

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9VF20

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Early endosome membrane
Endoplasmic reticulum membrane
; Multi-pass membrane protein
Endosome membrane
; Multi-pass membrane protein
Golgi apparatus membrane
; Multi-pass membrane protein
Late endosome membrane
Lysosome membrane
Melanosome membrane
Mitochondrion outer membrane
; Multi-pass membrane protein
Secreted, extracellular exosome

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-47Helical
Transmembrane67-85Helical
Transmembrane97-119Helical
Transmembrane135-154Helical
Transmembrane174-192Helical
Transmembrane245-271Helical
Transmembrane291-311Helical
Transmembrane368-390Helical
Transmembrane396-417Helical
Transmembrane488-506Helical

Keywords

PTM/Processing

Keywords

Proteomic databases

Expression

Gene expression databases

    • FBgn0038376Expressed in adult Malpighian tubule (Drosophila) and 147 other cell types or tissues

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain252-542ABC transmembrane type-1
Domain576-810ABC transporter
Region818-866Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    866
  • Mass (Da)
    97,886
  • Last updated
    2000-05-01 v1
  • Checksum
    625A6C8BA7679193
MLYCPPNVTLSEVWTQHGISHCFMDTVGPAVYGGFLLLFGSIQLLMYRKYATRITDPTQISKSRLFAMQLFLLLLLPVLALLRFLMNARIYPDSAVYGYMIFSTCVVCFSYPFSICLILKERYYQLPSMPTRGHGLVLLLFWTLAFINESLAFINLRHEDWWFHLKTNKDQIEMGLFVTRFLCSLLIFVLGLKAPGIMAPYNPHQRLDNDTANESQGNVQTGSAFRNGWRKLRTVFPYLWPKKNIALQIAVIVCIILLLAGRVIKLFLPIYRKKLVDSLTIAPIVFRWDFVLIYVALSFLQGGGTGSMGLFNNLRTFLWIRVQQYTTREIEIELFRHLHQLSLRWHLQRKTGEVLRVMDRGTDSINNLLNYIVFSIAPTILDLLVAVAYFVYAFNWWFGLIVFLTMFLYIASTIAITEWRTKYQRRMNLADNEQRARSVDSLLNFETVKYYGAEHYEVDCYREAILKYQKEEFLSMLTLNMLNTAQNIILCLGLLAGSLLCVYLVVHHQTLTVGDFVLFSTYLMELYMPLNWFGTYYRAIQKNFVDMENMFDLLKEEEEIVDAPGCSPLLTAGGGIEFSNVTFGYSPEKIVLRNVSFTVPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAILIDGQNIKLVQQQSLRKAIGVVPQDTVLFNNTIFYNIEYAKLGASDEAVYEAARAADIHERILGFPEKYETKVGERGLRLSGGEKQRVAIARTLLKAPIIVLLDEATSALDTHTERNIQAALARVCANRTTIIVAHRLSTIIHADEILVLQQGSIAERGRHEELVLREDGIYADMWQQQLKNLDAEQSGGSDNGDASAESGSEKRRAGGAGGPSGTGTGGAHFRAGHAHGGAR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014297
EMBL· GenBank· DDBJ
AAF55241.1
EMBL· GenBank· DDBJ
Genomic DNA
AY084209
EMBL· GenBank· DDBJ
AAL89947.1
EMBL· GenBank· DDBJ
mRNA
EU571211
EMBL· GenBank· DDBJ
ACE60575.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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