Q9VDJ9 · Q9VDJ9_DROME

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site1761ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcell body
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentdendritic branch point
Cellular Componentdendritic shaft
Cellular ComponentGolgi stack
Cellular Componentlate endosome membrane
Cellular Componentlysosomal membrane
Cellular Componentneuromuscular junction
Cellular Componenttype I terminal bouton
Molecular FunctionATP binding
Molecular FunctionGTP binding
Molecular Functionhistone H2AS1 kinase activity
Molecular Functionprotein kinase activity
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionsmall GTPase binding
Biological Processautophagy
Biological Processaxo-dendritic transport
Biological Processcell communication
Biological Processcell differentiation
Biological Processcellular response to starvation
Biological Processestablishment of Golgi localization
Biological Processintracellular distribution of mitochondria
Biological Processlocomotion
Biological Processlysosome localization
Biological Processnegative regulation of dendrite morphogenesis
Biological Processneuromuscular junction development
Biological Processprotein phosphorylation
Biological Processregulation of autophagosome assembly
Biological Processregulation of microtubule cytoskeleton organization
Biological Processregulation of signal transduction
Biological Processregulation of synapse maturation
Biological Processregulation of synaptic vesicle endocytosis
Biological Processregulation of terminal button organization
Biological Processresponse to endoplasmic reticulum stress
Biological Processretrograde transport, endosome to Golgi
Biological Processsynapse organization

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      Lrrk
    • Synonyms
      CT17358
      , dLRRK
      , dLrrk
      , dLRRK2
      , dLrrk2
      , Dmel\CG5483
      , LRRK
      , lrrk
      , LRRK2
      , Lrrk2
    • ORF names
      CG5483
      , Dmel_CG5483

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9VDJ9
  • Secondary accessions
    • Q0Q7G2

Proteomes

Organism-specific databases

PTM/Processing

Proteomic databases

Expression

Gene expression databases

    • FBgn0038816Expressed in second segment of antenna (Drosophila) and 27 other cell types or tissues

Family & Domains

Features

Showing features for repeat, domain, region.

TypeIDPosition(s)Description
Repeat291-323ANK
Domain919-1147Roc
Region949-988Disordered
Region1633-1666Disordered
Domain1728-2034Protein kinase
Region2095-2115Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,445
  • Mass (Da)
    271,521
  • Last updated
    2007-12-04 v3
  • Checksum
    A4531E16C103C33F
MEHPKTGTETALEACDYFVDEVIEASSIRDAREEVRQIKHGELRTAVISGDERTVRVLLAALGTERQIIVNMAPSGANTLLFLACQSGYESITQRLLDAGADGRSHAVTKYSPLYAAVHSGHLGIARLMLDHFPELIQQPTVERWLPLHAACINGHIKLLELLISYSYPDYLYQTYRDEEGQWEWRLPFDANAHDVTGQTSLYIASILGNKQLVGVLLKWQLHCRRTLGDSASSVSTPITPTRKRISFGIQAIMSKLHISGESEGPDDLASQESTECQRCPINVNLLCGAARETALLAAVRGGHLDVVQSLLQHGANPNIVAKPVEDHNDPKCCEEIYGLSNVPIAEACKQRSLAMLDLLLKHGARDDNGTAIGMAITCGDEAILSRLLARRVHPDSDYKINKKGLPTPVEVNVFLPSTSNISYSAMFPNNPTIIDWHSMGSSVQLSVVRVPWMVSGVLLLNPKLQSHPRLNEVALTAITRIDFSHNVLTSIPQELFHLVSLRYLNVAQNKITDLPAPIGQTYGCPVLDELFLQDNQLTTLPAAIFHLPALSILDVSNNKLQQLPFDLWRAPKLRELNVAFNLLRDLPVPPMQTSSSLLSLDKLNLQSFEEPPSNKPRNVTQQRLTHRNLWSATLDITDNDMKWQHEQDLGDGKTAGVGSSQLSSLNIANNLFTSIPAALPCLAVNLTRLNMSYNSLRSMGHVTSYPATLKQLDLSHNEISCWPSLPRITESDPHLLCYSCVQLPEGRDDDYKTASSKGSSSSATSFRASVLKSVCRHRRHLRLEALRTLILADNLLTRIQLSTDDATTLFNESEDADWSVVGVNRSKVIFPNLSMLDMTNNCLKEIPASLHELSSLSVLNISGNVNITELPPHLGLLSRLWNLNTRGCLLQEPLRSMIESKKHKTMDIVGYLKSIYEDAQPYARMKLMVVGVAGIGKSTLLDLLRQGAGSGSSSSSHRSRASENHWAKRMGHARSTSRSHRHSSASSANISTVGVDIGTWICEKRKRAPGSHGPVVFRTWDFGGQKEYYATHQYFLSKRSLYLVLWRISDGHKGLAELLQWLGNIQARAPNSPVIIVGTHFDAVGESISPQKAEQLQQLIREKFIAIPDAEKIGLPRVIDSIEISCRTLHNIHLLANIIYDTAMQLRSPGSKEPMLLQKIPASYIALEDIVNVIACNLRAAGRDPVLDGEQYKRLVTEQMRLHNYKSFRDAAELQQATTWCHENGVLLHYDDATLRDYYFLDPQWLCDMLAHVVTVREINPFAPTGVMKLDDLQMLFRSVQVQGNGNRSYIVSLLNKFEVALTWDSRTLLIPSLLPSQEAATPNSGSTVKLSQRSRGRSLGCSVSQEVNLNNLIYEQRSAPSSSSSSASVSQGLRRILLMTYFPSGFWSRLITRILADEQIIEAIRGVYMASQDYADFDLRTSLEQDTQWNLWQTGLALYYGPILIFKIWEVPFQKTERTQPFRTDGNRFKLKQDGIWSDVNLSSSSILEVYFPLYEVNISQEVDDNERQLLAEIRPHMSQVAKLLALTVDHIDLLLEDWYPSLGTRFVHTSEGRFLITRLVLCPRCLWKLQLQQNNEPSDREVPPVGCNRPSRSSRRGAGAYFLHGVGDPGEDGALNVFSAYLNATARRERRSEDSLGAGSDADSGVGPDSAGSSRNTSVDGHPGYHLPDNSNVCYAWMIEECILSVYNQSKISCPVHLEQSMAQLAPDVIFADIPDKHTIPSECIIKGSLLGRGAFGFVFKANCKVRGARSFKPVAMKMLQPVPPGARAKESALMAFKVAVGKWDRDPLQHSCKAYCTARQELAVLLTLKHPNIVPLVGICIKPLALVLELAPLGGLDALLRHYRRSGAHMGPHTFQTLVLQAARAIEYLHRRRIIYRDLKSENVLVWELPQPHTEDSPRNLVHIKIADYGISRQTAPSGAKGFGGTEGFMAPEIIRYNGEEEYTEKVDCFSFGMFIYENISLRQPFEGHESIKECILEGSRPALTQRETQFPTCCLDLMVLCWHEQPRRRPTASQIVSILSAPECIHLLDVVAMPHSEKIVCGVFQSLVGMGDDERCGLELWLPSFGSRIDILDCSPSGSLLQCNSISCSPQPQVAPPKTPENGANSRARSAQRLPKMNMLCCCLVGEAIWMGDVSGNLHAYSTSTYAHLFSYMLDPNIKSAVISLVYMEKIARVAVGTHNGRVFLVDATQMPSNCAFAEGSFVLTEICSGFVLHAACSVVVDGIYELWCGEIAGKINVFPLNENGVSGHQALCHSEEPNLIEDVKVARMCSNESHVFSCLYPGCMVYQWDVISKRIENKLDCSKLLPCSESLQSIAIDEHVNLIKCQISALAAHNSELYIGTTWGCLIVAELHTLRPISVFRPYENEIKSIITLSKDNVPLIATIGRRYRSLISRYVDSAESSTKSSAVSTPTHGAAKSVPPADVDNHIHCLLWRAKHWT

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0B4KHT3A0A0B4KHT3_DROMELrrk2513
A0A0B4KH16A0A0B4KH16_DROMELrrk2422

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014297
EMBL· GenBank· DDBJ
AAF55793.3
EMBL· GenBank· DDBJ
Genomic DNA
DQ494533
EMBL· GenBank· DDBJ
ABF29833.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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