Q9VCH1 · Q9VCH1_DROME

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenteukaryotic translation initiation factor 4F complex
Molecular FunctionmRNA binding
Molecular FunctionRNA 7-methylguanosine cap binding
Molecular Functiontranslation initiation factor activity
Biological Processmale meiotic nuclear division
Biological Processspermatogenesis
Biological Processtranslational initiation

Keywords

Enzyme and pathway databases

    • R-DME-1169408ISG15 antiviral mechanism
    • R-DME-156827L13a-mediated translational silencing of Ceruloplasmin expression
    • R-DME-166208mTORC1-mediated signalling
    • R-DME-72649Translation initiation complex formation
    • R-DME-72662Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

Names & Taxonomy

Protein names

  • Submitted names
    • Eukaryotic translation initiation factor 4G2, isoform A
    • Eukaryotic translation initiation factor 4G2, isoform C

Gene names

    • Name
      eIF4G2
    • Synonyms
      Dmel\CG10192
      , eIF4G
      , eIF4G-2
      , ms(3)nc32
      , nc32
      , ofs
    • ORF names
      CG10192
      , Dmel_CG10192

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9VCH1

Proteomes

Organism-specific databases

PTM/Processing

Proteomic databases

Expression

Gene expression databases

    • FBgn0260634Expressed in adult differentiating enterocyte in digestive tract and 276 other cell types or tissues

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-48Disordered
Compositional bias9-27Polar residues
Region231-306Disordered
Compositional bias267-306Polar residues
Region370-404Disordered
Compositional bias390-404Polar residues
Region664-745Disordered
Compositional bias682-745Polar residues
Region786-837Disordered
Compositional bias796-810Basic and acidic residues
Compositional bias811-837Polar residues
Region851-895Disordered
Compositional bias911-927Polar residues
Region911-947Disordered
Compositional bias928-947Basic and acidic residues
Compositional bias1046-1061Polar residues
Region1046-1065Disordered
Region1072-1119Disordered
Compositional bias1073-1090Polar residues
Region1181-1224Disordered
Compositional bias1203-1224Polar residues
Region1521-1618Disordered
Compositional bias1533-1547Basic and acidic residues
Compositional bias1548-1564Polar residues
Compositional bias1588-1618Polar residues
Compositional bias1635-1652Polar residues
Region1635-1656Disordered
Domain1696-1821MI

Sequence similarities

Belongs to the eukaryotic initiation factor 4G family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,072
  • Mass (Da)
    226,597
  • Last updated
    2002-10-01 v2
  • Checksum
    A8DEF55D5B3F25D8
MFPQQGGGGKGTRPQSTHQQNHNHQAQHHQATHSHHHHLQQQQEQQQSHAVFVPNHSGLHHHQQQHLLQQQQQQHQQQAAVAAAHLQQHIQQQQQQQVQAQAQAHHQPVIFYNTQPSYAAHSAAVNNSANGGGATLQLSAAASSNTLGHPLTGGHHGGANGVAPGSNMPRALSNPTLPPHFQQSAGLIAPAGGNAGGPYISATYIPINQTGPLMGMQPAVTFPTNGAAGASFYAAAPPPPQQKQLPPTAQQQGPGGAPGAAQTPTLAYYQLGPNAQNSAGNNVVSGANTHRGNMRGGQRSTPTAQHTNYFTAYTMAPGNAQRPAPTNVAPMMNSRSGALNGAAAFHHLPHNFGIPSLALGPPAGMTTPILAPAGMQAPPPQPPGGLHTFAPHLQSNSATTLPSVPSVTGVPAVASGFSTTSLPTPSVTTAPQLGANSDKVCKRKYAIPIIHPDTMENVMDGWKRSVFIKKDSNSTLTQHTDLDTALDDNSTLCLYQAPTLMDSGSGSSLLSGAMVDQQMQTVKPASSLKQSVSLEKVPEAVYCKDAVGQDVHPSPPPKSTDKDQISVIVKDILAHSGNAEDHLSFWQYSDVDNVTETHNSLPLVQSDLPDTTDTCQQPVLFQEQAKKQRPKLANKQSTATPASIANDVAEAAASGCPGVSILSRGQSMVTPAGPSTPPPPSRVAQQKSTKSIVTTAVAASVKPTTGSPNRKSSIQAATSTTTSSGASSSTASTPTHASSKLKQQPVNNLQHGKQIPGKVSTPALPPTASRISAAVTLLAGTANITTTTNSSKKQRQAQKRARELEKKKQKSSITSTTSTQGQNNNGKGNGNGNAALEINTNSNNAATVTTTSMSTLTTTTTATAPTTKQETAAVDDKETAQPTTDTLSATSNNTKVSSILRDKKTMLNPKEQLTSHNNNNNNNNEDGIEAKVESDPESDIKDDSMSNITGEKSEKHLANEEIVAKFLQKDSPDTSVVHAETQQLQFLNSSSSVCEEDEPVPVISEGVTKTEENAEAEIKFGDFHEDPRNDTGFICSSTWSSSTISKAAEDDSSQSSRSADNVDCAPKVVEQISEEKSASSTKSSPVHKATGSGPGSPKTKELKSKSPSPIPVPQVPKNYRYSIETLRELAKRRDSRKPPMVPCQKGDCISQLFVSRQQQPQQHHGQHIQQYQHMSFNESLDYVPGKRGRGHGPNKKHHDQHQQMGGSSGMGSGSGGGGGISNSSQRHMDIIRVQLSLKEEIKLSECENAWQPGTLRRVSMAGGQDEDDDVEGVLKKVRGILNKLTPDNFEVLLKEMSSIKMDNEAKMTNVMLLIFEKTISEPNFAPTYARFCKVLFHEIKAENKSLFTSSLITRIQHEFESNVNDANAKSKKLQPTMERINQCSDPAKKAELRAEMEDLEYQFRRRAWGTVRFIGELFKLQSLTNDRVLNCVESLLEHGCEEKLEYMCKLLTTVGHLLESSLPEHYQLRDRIEKIFRRIQDIINRSRGTSHRQQVHIKISSRVRFMMQDVLDLRLRNWDQPATHQSGQQGGRGQRHKQHDDSKDQSHSTGGGRGGGMNQHQQSSTHHQHQKHNQHGHDGGNYFMQKMPNKQHHENQTLSIDPSKLRFSNSSATDDSIAKLGNSSHYQWRNVGNRPVSSTQVNASNAPPPTSLLKRPGQNYKFLPYQQPSAVAGTANAPAGGNKSNVEVNDAFDGKQCQGLITKLVEEALNTREWQPEVLSIWRSHSGSQQSKTLFHLLTDYLHKSTVKRQHRQACGNIFAYLMDKDAVEKEIFEEAYSRFGDDFPDLLVDVPNGWGYVFEFLGPIIHSGHLDLKDVWQRRWLDDFFFAERFVYAFVSYFVQEFGAAYARKLWHNDYKLDRGQLFWSDVRKYREFVQSHSFYFLDNGPGQNQGHAKVKAPTTPRSPVEHVERIRHLLAISCDMAIDYINTNVAINDKFVRQLTRFLCCDFALTVMTNTHNNIKSGGNSKPLQLNTESFRSCCTPLLRLCIDAQEALEIACIDEAVDALQQHFMTEYEDDMAAGETICSTFSVLYESEVIPKESFDKWYKLEMAHSRAYRRPFIDKLRGFIEEM

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias9-27Polar residues
Compositional bias267-306Polar residues
Compositional bias390-404Polar residues
Compositional bias682-745Polar residues
Compositional bias796-810Basic and acidic residues
Compositional bias811-837Polar residues
Compositional bias911-927Polar residues
Compositional bias928-947Basic and acidic residues
Compositional bias1046-1061Polar residues
Compositional bias1073-1090Polar residues
Compositional bias1203-1224Polar residues
Compositional bias1533-1547Basic and acidic residues
Compositional bias1548-1564Polar residues
Compositional bias1588-1618Polar residues
Compositional bias1635-1652Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014297
EMBL· GenBank· DDBJ
AAF56194.2
EMBL· GenBank· DDBJ
Genomic DNA
AE014297
EMBL· GenBank· DDBJ
AHN57488.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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